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OBJECTIVES To document and compare the costs of treatment of psoriasis with 2 established systemic agents that differ substantially in their unit costs: methotrexate vs cyclosporine. DESIGN Cost-minimization analysis within a randomized controlled trial. SETTING Outpatient dermatology department at an academic hospital. PATIENTS Adults with moderate to severe plaque psoriasis, with no pre...
BACKGROUND Current end-of-life hospital care can be of poor quality and high cost. High volume and/or specialist care, and standardized care with clinical practice guidelines, has improved outcomes and costs in other areas of cancer care. METHODS The objective of this study was to measure the impact of the palliative care unit (PCU) on the cost of care. The PCU is a dedicated 11-bed inpatient...
background: economic burden due to premature mortalities is significant both on health system and on the society as a whole. this study aimed to determine the productivity costs and years of potential life lost associated with five leading causes of death in iran from 2006 to 2010. methods: data on mortality by sex and age-groups due to five main leading causes of death (myocardial infarcti...
BACKGROUND/PURPOSE The influence of home- and clinic-based caring system on the economic burden of heart failure remains unknown. METHODS Between January 2004 and December 2004, chronic heart failure patients who were followed up by specialist nurse-led telephone visiting regularly were enrolled. Clinical and economic data half a year before enrollment were collected as control. RESULTS A t...
BACKGROUND AND OBJECTIVE In chronic disease, treatment effects and costs accumulate over time; hence, the choice of time horizon in cost-effectiveness analysis can be particularly important. In this article we analyse the dynamic changes in cumulative costs, effects and incremental cost effectiveness of two competing drug strategies in patients with early Parkinson's disease (PD). METHODS Thr...
BACKGROUND All clinical practice guidelines recommend thiazides as a first-choice drug for the management of uncomplicated hypertension. Thiazides are also the lowest priced antihypertensive drugs. Despite this, the use of thiazides is much lower than that of other drug-classes. We wanted to estimate the potential for savings if thiazides were used as the first choice drug for the management of...
we show that when both sources ( lepton flavor violation sources and cp-violating phases) are present, the electric dipole moment of the electron, $d_e$, receives a contribution from the phase of the trilinear $a$-term of staus, $phi_{a_ au}$. for $phi_{a_ au}=pi/2$, the value of $d_e$, depending on the ratios of the lfv mass elements, can range between zero and three orders of magnitude a...
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