نتایج جستجو برای: 275 and 66
تعداد نتایج: 16839353 فیلتر نتایج به سال:
PURPOSE Histone deacetylase (HDAC) inhibitors are undergoing clinical evaluation in cancer therapy. Because HDAC modulation has been shown to enhance the radiosensitivity of tumor cells in vitro, we investigated the effects of the HDAC inhibitor MS-275 on the radioresponse of DU145 prostate carcinoma xenografts. EXPERIMENTAL DESIGN As an indicator of HDAC inhibition in vivo, the histone acety...
MS-275 (entinostat) is a histone deacetylase (HDAC) inhibitor currently in clinical trials for the treatment of several types of cancer.Recent reports have noted thatMS275 can cross the blood-brain barrier (BBB) and cause region-specific changes in rodent brain histone acetylation. To characterize the pharmacokinetics and distribution of MS-275 in the brain using positron emission tomography (P...
(1) Background: SARS-CoV-2 T cell immunity is rapidly activated following infection and vaccination crucial for controlling progression severity. The aim of the present study was to compare levels responses between cohorts subjects with hybrid (convalescent vaccinated), vaccinated naïve (non-exposed) convalescent unvaccinated subjects. (2) Methods: We performed a retrospective descriptive analy...
We hypothesized that bmo-miR-275 has a potential regulatory function regarding the expression of sericin gene 2 (BmSer-2). First, we examined the expression of bmo-miR-275 and its target gene BmSer-2 in seven different tissues from 5th instar day-3 silkworm larvae. The results showed that they were both specifically expressed in the middle silk gland, implying that spatio-temporal conditions ar...
1 Experimental Virtual Environments for Neuroscience and Technology Laboratory, Facultat de Psicologia, Universitat de Barcelona, Barcelona, Spain 2 CERMA UMR CNRS 1563, École Centrale de Nantes, Nantes, France 3 Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA 4 Institut d’Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Barcelona, Spai...
در این کار حلالیت تعدادی از گازها در یک فیلم خیلی نازک (نانومتری) پلی آمید 66 در تماس با صفحه ی گرافینی از یک سمت و در تماس با خلاء از سوی دیگر به کمک شبیه سازی دینامیک مولکولی محاسبه شده است.
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