Cottonseed cake in South East Asia has been associated with health issues in ruminants in the recent years. The present study was carried out to investigate the health issues associated with cottonseed cake feeding in dairy animals in Pakistan. All the cake samples were confirmed to be from early maturing cotton varieties (maturing prior to or during Monsoon). A survey of the resource persons i...

A survey of boneless hams processed in elastic rubber nettings showed that 32 of 59 contained over 100 ppb Nnitrosodibenzylamine (NDBzA) on the surface. These findings demonstrated the need to reduce the nitrosamine content. Nettings made with rubber thread reformulated with zinc diisobutyldithiocarbamate vulcanizing agent were evaluated for their effect on reducing the nitrosamine content. The...

Canned tuna (n = 240), salmon (n = 16), and mackerel (n = 16) were analyzed for mercury and fatty acids. Average mercury levels were 188, 45, and 55 ppb, respectively, and below the FDA Action Level of 1000 ppb. “Light tuna in water” contained lower mercury (x = 54 ppb) compared with “white/albacore tuna in water,” which contained higher eicosapentaenoic acid/docosahexaenoic acid (EPA/DHA) x = ...

RATIONALE Cardiac myosin-binding protein-C (cMyBP-C) phosphorylation at Ser-273, Ser-282, and Ser-302 regulates myocardial contractility. In vitro and in vivo experiments suggest the nonequivalence of these sites and the potential importance of Ser-282 phosphorylation in modulating the protein's overall phosphorylation and myocardial function. OBJECTIVE To determine whether complete cMyBP-C p...

We have reported previously that a partially purified bacteriocin (PPB) from Escherichia coli HSCio is toxic to Kill cells growing in vivo as micrometastases but apparently has no activity against a tumor growing i.m. We report here experiments to investigate possible reasons for this difference. The PPB was shown to become less effective against micro metastases, initiated by i.v. injection of...

Neonicotinoid insecticides are nicotinic acetylcholine receptor agonists used worldwide. Their environmental health effects including neurotoxicity are of concern. We previously determined a metabolite of acetamiprid, N-desmethyl-acetamiprid in the urine of a patient, who exhibited some typical symptoms including neurological findings. We sought to investigate the association between urinary N-...

We have reported previously that a partially purified bacteriocin (PPB) from Escherichia coli HSC10 is toxic to KHT cells growing in vivo as micrometastases but apparently has no activity against a tumor growing i.m. We report here experiments to investigate possible reasons for this difference. The PPB was shown to become less effective against micrometastases, initiated by i.v. injection of K...

New approaches to block the function of tumor stromal cells such as cancer-associated fibroblasts and pericytes is an emerging field in cancer therapeutics as these cells play a crucial role in promoting angiogenesis and tumor growth via paracrine signals. Because of immunomodulatory and other antitumor activities, IFNg , a pleiotropic cytokine, has been used as an anticancer agent in clinical ...

4. Automated Interpretation of CID Spectra 282 5. Accurate Mass Tags 282 C. Protein Identification in Complex Mixtures 282 D. Analysis of Protein Expression 284 III. Proteomes and Post-Translational Modifications 285 A. Proteomes 285 1. The Analytical Challenge 285 2. Analysis of Protein−Protein Complexes 286 B. Post-Translational Modifications 286 1. Background 286 2. Detection and Purificatio...

Ultrasensitive gas sensor based on epitaxial graphene on SiC has been fabricated. The sensor exhibits strong and reproducible response to nitrogen dioxide (NO2) in the concentration in air down to 1 part-per billion (ppb). Prototype of the transportable device for environmental monitoring allows fast and reproducible measurements of NO2 concentration in the range typical for environmental pollu...