OBJECTIVES This study aimed to cross-culturally translate the Qualiveen-30 into Persian and validate it in Iranian patients with spinal cord injury (SCI) and multiple sclerosis (MS). METHODS This was a cross-sectional prospective validation study. The translation and cross-cultural adaptation of the original questionnaire was performed in accordance with published guidelines. A total of 154 p...

Background:  Adolescent idiopathic scoliosis (AIS) may lead to physical and mental problems. It also can adversely affect patient satisfaction and the quality of life. In this study, we assessed the outcomes and satisfaction rate after surgical treatment of AIS using scoliosis research society-30 questionnaire (SRS-30).   Methods:  We enrolled 135 patients with AIS undergoing corrective surgery...

Background. Clinical trials in cancer frequently include cancer-specific measures of health but not preferencebased measures such as the EQ-5D that are suitable for economic evaluation. Mapping functions have been developed to predict EQ-5D values from these measures, but there is considerable uncertainty about the most appropriate model to use, and many existing models are poor at predicting E...

BACKGROUND Surgical management of suspected LGG remains controversial. A key factor when deciding a surgical strategy is often the tumors' perceived relationship to eloquent brain regions OBJECTIVE To study the association between tumor location, survival and long-term health related quality of life (HRQL) in patients with supratentorial low-grade gliomas (LGG). METHODS Adults (≥18 years) o...

9098 Background: Routine follow-up after curative treatment for early breast cancer exists to monitor for local recurrence and provide support for patients. Hospital visits can be stressful for patients and evidence indicates most recurrences are first identified by the patient. The value of resource-intense clinical follow-up is constantly being questioned. Many believe that time spent seeing ...

Background Due to its capability to secrete large quantities of plant biomass degrading enzymes (PBDE), Trichoderma reesei is widely applied for industrial purposes. In nature, expression of PBDE is efficiently regulated in this fungus. Several factors involved in this regulatory network have been identified. However, most of them are transcription factors. Long noncoding RNAs (lncRNAs) emerged...

Introduction: Fatigue is a common and frequently disabling symptom in cancer patients and cancer survivors. Fatigue may be caused by the disease itself, by treatment for the disease, by physical symptoms or conditions resulting from the disease or its treatment. The aim of this study was to assess fatigue and related factors in breast cancer patients. Material & Methods: We conducted a cross-se...

Citrus is the first tree crop in terms of fruit production. The colour of Citrus fruit is one of the main quality attributes, caused by the accumulation of carotenoids and their derivative C30 apocarotenoids, mainly β-citraurin (3-hydroxy-β-apo-8'-carotenal), which provide an attractive orange-reddish tint to the peel of oranges and Mandarins. Though carotenoid biosynthesis and its regulation h...

Methods The JAMAR includes: Juvenile Arthritis Functionality Scale (JAFS) (0 = normal; 30 = worst), Pediatric Rheumatology Quality of Life (PRQL) questionnaire (0 = best; 30 = worst); visual analogue scales (0 = best; 10 = worst) for parent/patient rating of well-being (WB), pain (P), disease activity (DA); parent/patient assessment of morning stiffness, disease status, satisfaction about disea...

A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 μg/mL.