To achieve selective inhibition of cytosolic and membrane-bound carbonic anhydrase (CA II and CA IV, respectively), we synthesized a polymer of molecular weight 3500 from polyoxyethylene bis acetic acid and aminobenzolamide. The new compound, designated F (for Florida) 3500, is stable, water soluble and nontoxic. It is excreted largely unchanged by glomerular filtration. The Ki at 37 degrees C ...

in the early of 1st millennium bc, in the region of lorestan, iran, the ellipi kingdom formed and played a significant role in regional developments, particularly in relation with two rival governments, assyria and elam. the political history reconstruction of the ellipi kingdom is more reliant on assyrian resources which cover just very short and particular part of its life. the first recorded...

The aim of the paper is to present a project of a syntactically annotated corpus of Hittite, a dead cuneiform language (Anatolian family), the oldest Indo-European language attested in writing, that was spoken in 18-12 cc. BC on the territory of present-day Turkey. No publicly available corpus of Hittite with syntactic annotation exists so far, meanwhile Hittite syntax proves to be more and mor...

Abstract This multi-proxy approach combines results of sedimentological, pollen and diatom studies on sediments Lake Wonieść, Greater Poland. enables reconstruction the natural anthropogenic drivers past environmental change. Several steps lake development are recorded, from a eutrophic to an oligotrophic stage, with increasing human influence back hypereutrophic one. Human in form eutrophicati...

The use of Ḥijāmah dates back to 3500 BC in Egypt, with records Ebers Papyrus. But the last two decades, is gaining its due acceptance management different neuromuscular and pain disorders. For sciatica, advised over sciatic nerve. 2 cups (over gluteal area thigh/ calf muscle below ankle), 5 even 9 may be done patients sciatica. These settings/ protocols sciatica show a significant reduction di...