The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families or from different species with a special emphasis on inferring evolutionary relationships and patterns of DNA and protein evolution. In addition to the tools for statistical analysis of data, MEGA provides many conven...

Summary : Detecting significant associations between genetic variants and disease may prove particularly challenging when the variants are rare in the population and/or act together with other variants to cause the disease. We have developed a statistical framework named Mutation Enrichment Gene set Analysis of Variants (MEGA-V) that specifically detects the enrichments of genetic alterations w...

A new robust clustering scheme based on fuzzy c-means is proposed and the concept of a fuzzy mega-cluster is introduced in this paper. The fuzzy mega-cluster is conceptually similar to the noise cluster, designed to group outliers in a separate cluster. This proposed scheme, called the mega-clustering algorithm is shown to be robust against outliers. Another interesting property is its ability ...

Mega-projects figure prominently in the arsenal of contemporary city-building strategies. The allure is of a city redefined, placed on the world stage and able to improve services, facilities and revenues. Community attitudes to such projects are often mixed, with fears of gentrification, displacement or loss of existing city character. Although mega-projects are adopted to pursue global ambiti...

In various fields of computer science, rapidly growing hardware power, such as high-speed network, high-performance CPU, huge disk capacity, and large memory space, has been fruitfully harnessed. Examples of such usage are large scale data and web mining, grid computing, and multimedia environments. We propose that such rich hardware can also catapult software engineering to the next level. Hug...

The goal of the Medium Energy Gamma-ray Astronomy (MEGA) telescope is to improve sensitivity at medium gamma-ray energies (0.4–50 MeV) by at least an order of magnitude over that of COMPTEL. This will be achieved with a new compact design that allows for a very wide field of view, permitting a sensitive all-sky survey and the monitoring of transient and variable sources. The key science objecti...

The article considers the possibility of developing a diet that provides an athlete with adequate level biologically active substances antioxidant effect. losses total content antioxidants in composition food products plant origin during heat treatment steam convection apparatus were determined and amounted to 16.9 heat-treated beets; 14.8% cabbage; 34.6% potatoes carrots; 20.5% onion; 22.7% ro...

Introduction: Fasting, like Islamic Ramadan Fasting, has been associated with health benefits. Islamic Ramadan fasting, a form of caloric restriction (CR) or alternate day fasting that. Studies suggest a comparable effect of ADF and caloric restriction. Despite the fact that fasting can be considered as a form of dietary restriction, fasters tend to have difficulty to reduce their food intake d...

The Senate Finance Committee’s hearing on July 28, 2021 -- Building Bipartisan Retirement Legislation: How Can Congress Help? spotlighted “mega-IRAs”: individual retirement accounts with balances of $5 million or more. An analysis by the Joint Committee Taxation in advance 28 found that number taxpayers mega-IRAs now exceeds 28,000. followed a June report nonprofit investigative journalism orga...