Based on comparative phylogenetic analysis of 16S rRNA gene sequences deposited in an RDP database, we constructed a local database of thaumarchaeotal 16S rRNA gene sequences and developed a novel PCR primer specific for the archaeal phylum Thaumarchaeota. Among 9,727 quality-filtered (chimeral-checked, size >1.2 kb) archaeal sequences downloaded from the RDP database, 1,549 thaumarchaeotal seq...

The capsid proteins VP2 and VP3 of infectious bursal disease virus, a birnavirus, are derived from the processing of a large polyprotein: NH2-pVP2-VP4-VP3-COOH. Although the primary cleavage sites at the pVP2-VP4 and VP4-VP3 junctions have been identified, the proteolytic cascade involved in the processing of this polyprotein is not yet fully understood, particularly the maturation of pVP2. By ...

The microtubule-associated protein AtMAP65-1 from Arabidopsis thaliana dimerizes and forms 25 nm cross-bridges between microtubules, but the exact mechanism is unknown. Here, we used the predicted three-dimensional structure of AtMAP65-1 as a basis for analyzing the actual cross-bridging in detail. Fold-recognition predicts that AtMAP65-1 contains four coiled-coil domains and a flexible extende...

Wolfgang Behringer, Thurn und Taxis. Die Geschichte ihrer Post Unternehmen, München, Zürich (Piper) 1990, 494 S.

The secondary use of electronic health records opens up new perspectives. They provide researchers with structured data and unstructured data, including free text reports. Many applications been developed to leverage knowledge from free-text reports, but manual review of documents is still a complex process. We developed FASTVISU a web-based application to assist clinicians in reviewing documen...

Background: Sudden hearing loss is a result of various factors. Most therapies aim to improve the cochlear microcirculation but effectiveness is not sufficiently documented. Methods: 741 patients were included into the non-interventional observation thus far and analyzed with regard to various therapies and time progressions. The main outcome measure consisted of hearing threshold difference be...

Although the variability of dream content is large, typical dream themes that occur quite often and are reported by many people can be identified (e.g., being chased, falling, flying, failing an examination, being unable to find a toilet or restroom). The present study is an investigation of the stability of the rank order of the dream themes and of gender differences in the content of dreams. ...

CSE 494/598 Hemal Khatri Overview This goal of this project is to mine patterns in the search results by clustering the search results. The different methods used for clustering are: 1. K-Means 2. Buckshot 3. Bisecting K-Means. For each of these methods, we show the algorithm used for computing the clusters as well as the time complexity for each of these algorithms. We also compare the quality...