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تعداد نتایج: 2538114 فیلتر نتایج به سال:
A simple, solvent-free, and field-compatible approach to sample preparation is provided by the basic process known as solid-phase micro extraction (SPME). The aim of this study was improve circumstances under which triazines were extracted from aqueous matrices. complex technique enabled detection analytes in water at a physiological level. An evaluation practicability most commercially availab...
The nature of alpha adrenergic receptors in human cerebral arteries was characterized and alteration of these receptors after subarachnoid hemorrhage (SAH) was examined using a radioligand binding assay. The specific 3H-prazosin binding to human cerebral arteries was saturable and of high affinity (KD = 4.1 nM) with a Bmax of 92 fmol/mg protein. Specific 3H-yohimbine binding to these tissues wa...
This study examined the effect of intracarotid oleic acid infusion on blood-brain barrier permeability. Oleic acid was infused for 30 s at a rate of 6 ml/min into the right internal carotid artery at concentrations of 10(-6), 10(-5), 2 x 10(-5) and 5 10(-5) M. Extensive Evans blue-albumin extravasation was observed 15 min after the administration of 2 x 10(-5) M oleic acid. The permeability sur...
The positive inotropic effects of catecholamines have been postulated to result from an increase in the intracellular level of cyclic AMP (adenosine 3',5'-monophosphate) produced by activation of adenyl cyclase. Although lack of an inotropic effect by exogenously administered cyclic AMP has cast doubt on this hypothesis, cardiac cells are not readily permeable to cyclic AMP. The N-2'-O-dibutyry...
Methods 16 Patients with AF (7 with prior ablation, 9 with no history of ablation; 11 with paroxysmal AF, 5 with persistent AF) underwent CMR on a 1.5-T Siemens Avanto scanner. DE-LA images were acquired 15 min after contrast injection using a 3D inversion recovery, respiration-navigated, fat suppressed, ECG-gated, gradient echo pulse sequence, with acquisition parameters as follows: voxel size...
The role of phosphodiesterase in glucagon resistance of large adipocytes was investigated. A comparison was made of phosphodiesterase activities of homogenates prepared from isolated small (mean diameter approximately 45 micro m) and large (mean diameter approximately 78 micro m) adipocytes, using various concentrations (5 x 10(-4) to 1 x 10(-7) M) of 3',5'-cAMP. Kinetic analyses revealed two d...
Rabbit right ventricular papillary muscles were cooled from 30 to approximately 1 degree C immediately after discontinuing electrical stimulation (0.5 Hz). This produced a contracture that was 30-50% of the preceding twitch magnitude and required 20-30 s to develop. The contractures were identical in cooling solutions with normal (144 mM) or low (2.0 mM) Na. They were therefore not Na-withdrawa...
As reported elsewhere,' the study of RNA synthesis in vitro in immature duck erythrocytes has revealed the occurrence in the nucleus of fast turning-over RNA of high molecular weight (from 2 X 106 to 107, or possibly more) and with base composition different from that of ribosomal RNA, and characterized by a high U and relatively low GC content. No relationship of precursor-to-product typeor, a...
F. P. An,1 J. Z. Bai,1 A. B. Balantekin,2 H. R. Band,2 D. Beavis,3 W. Beriguete,3 M. Bishai,3 S. Blyth,4 K. Boddy,5 R. L. Brown,3 B. Cai,5 G. F. Cao,1 J. Cao,1 R. Carr,5 W. T. Chan,3 J. F. Chang,1 Y. Chang,4 C. Chasman,3 H. S. Chen,1 H. Y. Chen,6 S. J. Chen,7 S. M. Chen,8 X. C. Chen,9 X. H. Chen,1 X. S. Chen,1 Y. Chen,10 Y. X. Chen,11 J. J. Cherwinka,2 M. C. Chu,9 J. P. Cummings,12 Z. Y. Deng,1...
This study has examined the hypotheses that, firstly, the ethanol induces delayed cellular protection in mouse cardiac myocytes against subsequent sustained simulated ischemia (SI). Secondly, the delayed cyto-protective effect induced by the ethanol depends more on time than the dose in mouse cardiac myocytes. Finally, ethanol-induced delayed cellular protection in mouse cardiac myocytes is med...
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