Tyrosinase is a key enzyme in melanin formation. Its inhibition crucial step for hyperpigmentation reduction. The aim of this study was to evaluate the efficacy two plant flavonoids: ellagic acid and glabradin, on tyrosinase as well their whitenning properties vivo. For reason IC50 acid, glabradin mixture reaction estimated. Kojic served reference sample. In addition vivo an emulsion with 14 pa...