Many psychiatric disorders emerge during adolescence. The study of executive functions in animal models of these disorders critically requires short-duration tasks measuring these functions before the animal ages. Here, a novel 5-choice serial reaction time task (5-CSRTT) protocol is presented, to measure attention and impulsivity within one week, without scheduled food deprivation and with lit...

Aliphatic glucosinolates are the predominant sulfur-rich plant secondary metabolites in economically important Brassica crops. Glucosinolates and their hydrolysis products are involved in plant-microbe, plant-insect, plant-animal, and plant-human interactions. It is, therefore, important to manipulate glucosinolate profiles and contents in Brassica species. In this study, aliphatic glucosinolat...

Establishing prognosis proves particularly difficult with neuroendocrine tumours (NETs) as a benign looking histology can be associated with a malignant behaviour. In order to identify prognostic factors we examined 44 gastrointestinal and pulmonary, paraffin-embedded NETs histologically and immunohistochemically. DNA-image-cytometry was used to examine 40 of these. We found that poor different...

Models of long-term estrogen-deprived breast cancer cells are utilized in the laboratory to mimic clinical aromatase inhibitor-resistant breast cancer and serve as a tool to discover new therapeutic strategies. The MCF-7:5C and MCF-7:2A subclones were generated through long-term estrogen deprivation of estrogen receptor (ER)-positive MCF-7 cells, and represent anti-hormone‑resistant breast canc...

Chromatin organization can be probed by Chromosomal Capture (5C) data, from which the encounter probability (EP) between genomic sites is presented in a large matrix. This matrix is averaged over a large cell population, revealing diagonal blocks called Topological Associating Domains (TADs) that represent a sub-chromatin organization. To study the relation between chromatin organization and ge...

A series of some novel 1,2,4-triazol-5(4H)-one derivatives were designed and synthesized under microwave irradiation via multistep reaction. The structures of 1,2,4-triazoles were confirmed by (1)H NMR, MS, FTIR, and elemental analysis. The antifungal activities of 1,2,4-triazoles were determined. The antifungal activity results indicated that the compounds 5c, 5f, and 5h exhibited good activit...

We give sound and complete analytic tableau systems for the propositional bimodal logics KB, KB C , KB 5, and KB 5C . These logics have two universal modal operators K and B , where K stands for knowing and B stands for believing. The logic KB is a combination of the modal logic S5 (for K ) and KD45 (for B ) with the interaction axioms I : Kφ → Bφ and C : Bφ → K Bφ. The logics KB C , KB 5, KB 5...

We investigate the mass spectrum of pentaquark baryons with anticharm quark, in quenched lattice QCD with exact chiral symmetry. By chiral extrapolation to mπ = 135 MeV, we determine the masses of the lowest lying states of the antisextet (JΠ = 1/2+) and the triplet (JΠ = 1/2), in the isospin limit (mu = md). The masses of the antisextet are: 2977(109) MeV for the iso-singlet Θc([ud][ud]c̄); 318...

Black foot disease of grapevines is a major economic issue for the viticulture industry worldwide. The mainly associated with complex pathogen species within genera Dactylonectria and Ilyonectria. susceptibility six grapevine rootstock cultivars to black under field conditions was assessed. Callused rootstocks 101-14, 5C, 420A, Riparia Gloire, Schwarzmann 3309C were planted into soil containing...