James Robins,1,3 Andrea Rotnitzky,2,3 and Stijn Vansteelandt4 1Department of Epidemiology Harvard School of Public Health, 655 Huntington Avenue Boston, Massachusetts 02115, U.S.A. 2Department of Economics Universidad Torcuato di Tella Saenz Valiente 101

Background Within the tumor microenvironment, distinct CD4+ T cell subsets can play different and even opposite roles either promoting or suppressing anti-tumor responses through recognition of antigens presented by human leukocyte antigen (HLA) class II molecules. However, how cancers co-opt these processes to shape intratumoral landscape achieve immune evasion remains incompletely understood....

In this work a measurement of the muon intensity at the Waste Isolation Pilot Plant (WIPP) near Carlsbad, NM, USA is presented. WIPP is a salt mine with a depth of 655 m. The vertical muon flux was measured with a two panels scintillator coincidence setup to Φvert = (3.10 +0.05 −0.07) 10 −7 s−1cm−2sr−1.

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In considering the marketing of food products to children, the role of packaging warrants closer attention. The use of packaging as a marketing vehicle is evidently increasing. Marketing analysts suggest two reasons for this. First, many food choices are made at the point of sale, so ‘the package becomes a critical factor in [the] consumer decision-making process, because it communicates to con...