Basic principles of the neurobiology of aging were reviewed within selected topic areas chosen for their potential relevance to epileptogenesis in the aging brain. The availability of National Institute on Aging-supported aged mouse and rat strains and other biological resources for studies of aging and age-associated diseases was presented, and general principles of animal use in gerontologica...

Fishes and marine mammals may suffer a range of potential effects from exposure to intense underwater sound generated by anthropogenic activities such as pile driving, shipping, sonars, and underwater blasting. Several underwater sound recording (USR) devices have been built to acquire samples of the underwater sound generated by anthropogenic activities. Software becomes indispensable for proc...

Electrocardiogram (ECG) is a graphic recording of the electrical activity produced by the heart. The accuracy of any electrocardiogram waveform extraction plays a vital role in helping a better diagnosis of any heart related illnesses. We present a computer-aided application model for detection of cardiac arrhythmia in ECG signal, which consists of signal pre-processing and detection of the ECG...

The electrocardiogram (ECG) is one of the most important techniques for heart disease diagnosis. Many traditional methodologies of feature extraction and classification have been widely applied to ECG analysis. However, the effectiveness and efficiency of such methodologies remain to be improved, and much existing research did not consider the separation of training and testing samples from the...

Age-associated memory impairment (AAMI) occurs in many mammalian species, including humans. In contrast to Alzheimer's disease (AD), in which circuit disruption occurs through neuron death, AAMI is due to circuit and synapse disruption in the absence of significant neuron loss and thus may be more amenable to prevention or treatment. We have investigated the effects of aging on pyramidal neuron...

BACKGROUND Age-related cognitive decline (ARCD) is of major societal concern in an ageing population, with the development of dietary supplements providing a promising avenue for amelioration of associated deficits. Despite initial interest in the use of phospholipids (PLs) for ARCD, in recent years there has been a hiatus in such research. Because of safety concerns regarding PLs derived from ...

A dual-channel single-mode-multi-mode-single-mode (SMS) fiber optic sensor encapsulated by polydimethylsiloxane (PDMS) was proposed for the first time, simultaneous monitoring of brachial and radial arteries accurate blood pressure prediction. With help machine learning algorithm Support Vector Regression (SVR), SMS can continuously accurately monitor systolic diastolic pressure. Commercial sph...

The introduction of 24-hour ambulatory blood pressure measurement into clinical practice created a large market for ambulatory blood pressure measurement devices. Forty-three such devices from 31 manufacturers or suppliers are now available to satisfy a market demand that is likely to increase. The aim of this article is to identify the devices available and then to examine critically any valid...

Much like the health of the overall economy, salary growth in the healthcare technology management (HTM) field over the past two years has been a mixed bag, according to a 2012 AAMI employment survey. There were a few positive signs with some base salaries rising—with one type of job in particular seeing a significant salary increase—and more fringe benefits. But the salary growth was mostly mo...