despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat sciatic nerve gap. fifty- four male wistar rats were divided into three experimental groups (n = 18),...

background and objective: approximately 45% of benign peripheral nerve sheath tumors (pnst) occur in head and neck regions. malignant peripheral nerve sheath tumors (mpnst) are less common and only 8-15% of these tumors occur in head and neck region. in this study, we aimed at evaluating the demographic characteristics, pathologic findings, locations, main clinical presentations and family hist...

objective(s): we investigated the histopathological effects of metamizole sodium (ms) on the sciatic nerve.  materials and methods: this study was performed using 48 adult male wistar albino rats. ten groups were constituted with 6 rats in each group. ms injection into the sciatic nerve (group 1), ms injection into the muscle [group 3 (50 mg/kg, 0.4 ml) and group 5 (50 mg/kg, 0.8 ml)], ms injec...

introduction: intraparotid neurofibromas of the facial nerve are extremely rare and mostly associated with neurofibromatosis type 1 (nf1). case report: this is a case of a healthy 40-year-old man, which underwent surgery for a preoperatively diagnosed benign parotid gland lesion. after identification of the facial nerve main trunk, a single large mass (6 x 3 cm) incorporating the upper nerve di...

case report: we report a 44-year-old man with right femoral nerve palsy following delayed reduction of an anterior dislocation of hip. conclusion: two months after closed reduction, complete clinical recovery of right femoral nerve was achieved and the patient was able to resume his job. introduction: incidence of nerve injury in traumatic hip dislocations is up to 10 %. sciatic nerve is the mo...

lipomatosis of the nerve, also known as fibrolipomatous hamartoma, is characterized by the infiltration of the nerve by fibro-fatty tissue. the affected nerve becomes thicker, and it simulates a mass lesion. lipomatosis usually affects the median nerve and lipomatosis of the sciatic nerve is extremely rare. magnetic resonance imaging (mri) is the key to diagnosis, and it is usually pathognomoni...

The repair of peripheral nerve injuries is still one of the most challenging tasks and concerns in neurosurgery. Effect of methylprednisolone-laden hydrogel loaded into a chitosan conduit on the functional recovery of peripheral nerve using a rat sciatic nerve regeneration model was assessed. A 10-mm sciatic nerve defect was bridged using a chitosan conduit (CHIT/CGP-Hydrogel) filled with CGP-h...

Objective(s): To investigate the effect of topical administration of alpha-lipoic acid into chitosan conduit on peripheral nerve regeneration using a rat sciatic nerve transection model. Materials and Methods: Forty five Wistar rats were divided into three experimental groups randomly. A 10-mm gap of sciatic nerve was bridged with a chitosan conduit following surgical preparation and anesthesia...