Radioiodine therapy is known as the most effective treatment of differentiated thyroid carcinoma (DTC) to ablate remnant thyroid tissue after surgery. In patients with DTC treated with radioiodine, internal radiation dosimetry of radioiodine is useful for radiation risk assessment. The aim of this study is to describe a method to estimate the absorbed dose to the blood using medical internal ra...

Abstract. The goal of this project is to determine the absorbed dose of radiation to a patient using 99mTc-MAA as a tracer for a lung scan using the MIRD formula accounting only for the radiation dose contributed by the target organ. The radiation dose for other organs to the target organ is considered negligible as the uptake of 99mTc-MAA from other organs is less than 1%. In addition to calcu...

BACKGROUND The high-dose-rate (HDR) brachytherapy might be an effective tool for palliation of dysphagia. Because of some concerns about adverse effects due to absorbed radiation dose, it is important to estimate absorbed dose in risky organs during this treatment. OBJECTIVES This study aimed to measure the absorbed dose in the parotid, thyroid, and submandibular gland, eye, trachea, spinal c...

determination of the total body absorbed dose consists of two parts: beta radiation absorbed dose and gamma radiation absorbed dose. the first part is generally determined by clinical data, while the second part has a parameter called absorbed ratio and is determined by computational methods. the monte-carlo computational methods have been shown to be the most suitable in determination of the a...

The micronucleus assay in human peripheral blood lymphocytes is a sensitive indicator of radiation damage and could serve as a biological dosimeter in evaluating suspected overexposure to ionising radiation. Micronucleus (MN) frequency as a measure of chromosomal damage has also extensively been employed to quantify the effects of radiation dose rate on biological systems. Here we studied the e...

a 65 year old male with metastatic colorectal cancer (mcrc) in the liver was referred for selective internal radionuclide therapy (sirt) following a history of extensive systemic chemotherapy. 90y pet imaging was performed immediately after treatment and used to confirm lesion targeting and measure individual lesion absorbed doses. lesion dosimetry was highly predictive of eventual response in ...

The normoxic polymer gel dosimeter based on N-isopropyl acrylamide (NiPAM) is a promising full 3D-dosimeter with high spatial resolution and near tissue equivalency. NiPAM gel samples were irradiated to different doses using a linear accelerator. The absorbed dose was evaluated using MRI and statistical significance of the analysed data was calculated. The analysis was carried out using an in-h...