Osteoporosis is a characterized by low bone mass and microarchitectural deterioration, with a consequent increase in bone fragility [1]. Bone strength impairment leads to an increased risk of fracture, as strenght reflects the integration of bone quantity (bone mineral density, BMD) and bone quality [2]. Common sites of osteoporotic fractures are spine, hip, distal forearm and proximal homerus....

Assessment of bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA) plays a vital role in the diagnosis of osteoporosis and in monitoring a patient's response to drug therapy. This commentary will discuss controversies surrounding the use of DXA for screening and monitoring of BMD in women.