In the title compound, [RhCl(3)(CH(3)CN)(C(18)H(21)P)(2)]·2CH(3)CN, the complex mol-ecule lies on a twofold rotation axis that passes through the Rh(III) atom, one Cl atom, and the C and N atoms of the coordinated acetonitrile mol-ecule. The Rh(III) atom is coordinated by two P atoms in trans positions, three Cl atoms and an acetonitrile mol-ecule in a distorted octa-hedral geometry. Intra-mole...

Retention data for 29 alkaloids were determined on an amide embedded RP silica column with different aqueous mobile phases – mixtures of acetonitrile with water, mixtures of acetonitrile with aqueous buffers of pH 3 or pH 7.8, and mixtures of acetonitrile with aqueous buffers containing ion-pair reagents or silanol blockers. Improved peak symmetry and separation selectivity for basic solutes we...

Drug solubility is one of the most significant physicochemical properties as it related to drug design, formulation, quantification, recrystallization, and other processes, so understanding crucial for pharmaceutical industry. In this context, research presents thermodynamic analysis sulfadiazine (SD) in cosolvent mixtures {acetonitrile + 1-propanol} at 9 temperatures (278.15 K–318.15 K), which...