The authors present a rare case of double skin tumors: acral lentiginous melanoma and metatypical carcinoma. The tumors were manifested as gradually enlarging ulcerations on the leg and sole of the foot that did not respond to standard treatment. The skin biopsies showed advanced acral lentiginous melanoma on the sole and metatypical carcinoma of the lower leg. Soon after the diagnosis was made...

Acrodermatitis enteropathica is classified as a congenital autosomal recessive type and an acquired transient type. This disease manifests as acral and periorificial dermatitis, alopecia, intractable diarrhea, and failure to thrive. Whereas the autosomal hereditary type is caused by malabsorption of zinc in the intestine, the acquired type is caused by low nutritional support or decreased perip...

The incidence of EM is unclear, but it is thought to affect less than 1% of the population, with a slight predominance among young women.1 EM is characterised by targetoid lesions distributed in peripheral acral regions, and macular, papular and urticarial patterns peripherally and on the extensor surfaces, and, less frequently, diffusely on the trunk. Oral and genital lesions are generally pre...

BACKGROUND Acral peeling skin syndrome is a rare autosomal recessive genodermatosis due to a missense mutation in transglutaminase 5. The skin peeling occurs at the separation of the stratum corneum from the stratum granulosum. CASE PRESENTATION We present a case of two siblings who developed continuous peeling of the palms and soles from the first year of life. This peeling was more severe o...

On examination, there were multiple skin colored to erythematous and edematous papules of about 1 to 5 mm size [Figure 1]. Many of the lesions, located over the extensor aspects of hands [Figure 2], forearms, elbows and upper arms were topped with tiny crusts and scales whereas others showed a central dusky hue. Examination of the conjunctiva revealed mild icterus. Bilateral axillary, epitrochl...

Kindler syndrome is a rare autosomal recessive disorder characterized by acral blisters in infancy and early childhood, followed by photosensitivity, progressive poikiloderma and cutaneous atrophy. Other features include webbing of the toes and fingers, palmoplantar hyperkeratosis, gingival fragility, poor dentition, and mucosal involvement in the form of urethral, anal and oesophageal stenosis...

superficial acral fibromyxoma are rare soft tissue tumors predominantly involving hands and feet of adults. there are only a few reported cases of this benign neoplasm, but no fnac diagnosis of this tumor is reported in the literature. a forty-eight year old female presented with a 5 x 3.5 cm globular, firm swelling over the right fifth toe. fine needle aspiration cytology (fnac) of the lesion ...

The authors describe a case of a female patient with Acral Pseudolymphomatous Angiokeratoma of Children, known as APACHE. It is a rare benign cutaneous disease, of unknown etiology, characterized by multiple, asymptomatic erythematous-violaceous papules and nodules, usually located unilaterally with acral distribution. Today, this denomination is questionable, since there are published reports ...

Acral lentiginous melanoma (ALM) of the sole sometimes has a hyperkeratotic appearance and mimics a pigmented wart. We report a case of an 81-year-old woman with an ALM on the left sole with hyperkeratosis. Due to its presentation it was difficult to make a correct diagnosis at the beginning. Finally we noticed several small, pigmented macules around the wart-like lesion with the parallel ridge...