The causes of individuality of the plasma enzymes alanine aminotransferase (ALT; EC 2.6.1.2), aspartate aminotransferase (AST; EC 2.6.1.1) and gamma-glutamyl transferase (GGT; EC 2.3.2.2) were investigated in a study of 206 pairs of twins. Between-person variance was greater in men than women, while within-person variation was similar in both sexes. Plasma ALT and AST levels were affected by ge...

in the present study, we examined the antioxidative activities of satureja khuzestanica essential oil (ske) and possible protective effect of ske on lipid profile, atherogenic index and liver enzyme markers in alloxan-induced type 1 diabetic rats. thirty male rats were randomly divided into three groups; group one as control, group two diabetic untreatment, and group three treatments with ske b...

BACKGROUND Serum aminotransferase concentrations are reportedly strongly associated with insulin resistance, an established cardiovascular risk factor that is not routinely assessed in clinical practice. We therefore explored the possibility that serum aminotransferase concentrations are as closely related to large artery disease as insulin resistance in rheumatoid arthritis (RA). METHODS Car...

the present study was conducted to investigate the clinical effects and possible side effects of yarrow extract ( achillea millefolium l.) as feed additive on biochemical blood parameters and growth performance of rainbow trout ( oncorhynchus mykiss ). fishes were treated with 0 (control), 0.1, 0.5 and 1% of yarrow extract for 30 days. plasma alanine aminotransferase (alt), aspartate aminotrans...

aim : in the current study, we aimed at identifying independent laboratory parameter to predict liver damage. background : although liver biopsy is frequently recommended in assessing disease severity and selecting antiviral treatment candidates, it has several limitations. patients and methods : a total of 527 patients with untreated chronic hepatitis b virus infection were selected. a percuta...

The present study was designed to reveal the hitherto unknown efficacy of two commonly used hepatoprotective drugs, L-ornithine-L-aspartate (lornit) and silymarin in the regulation of kidney toxicity and thyroid dysfunction in mice. Renal and hepatic lipid peroxidation (LPO) was induced by the administration of carbon tetrachloride (CCl4) for 2 weeks (2.0 gm/kg twice a week). In two separate gr...

Although elevation of the levels of serum alanine aminotransferase (ALT) following liver injury is well known, confusion exists concerning skeletal muscle injury as the cause of this rise. We reviewed the records of 16 patients who had muscle necrosis without evidence of liver disease. The patients were divided into three groups: extreme exercise, polymyositis, and seizures. All patients exhibi...

Muscle injury is common in Florida manatees (Trichechus manatus latirostris). Plasma aspartate aminotransferase (AST) is frequently used to assess muscular damage in capture myopathy and traumatic injury. Therefore, accurate measurement of AST and alanine aminotransferase (ALT) is important in managed, free-ranging animals, as well as in those rehabilitating from injury. Activities of these enz...

a study was conducted to evaluate the effects of blood pressure medications on index of liver damage in ascites incidence in broilers. a completely randomized experimental design with a 2×3 factorial arrangement (sex and feed additive), with 3 replicates of 12 birds, with 216 (108 male and 108 female) one-day-old (ross 308) was applied. feed additive includes control (without feed additive) lev...