The purpose of this study was to identify clinical predictors and anatomical structures involved in patients with pain after dorsolateral medullary infarction. Eight out of 12 patients (67%) developed poststroke pain within 12 days to 24 months after infarction. The pain occurred in the ipsilateral face (6 patients) and/or the contralateral limbs and trunk (5 patients, 3 of whom also had facial...

The fifth and greatest cranial nerve, the trigeminal nerve (V), is in charge of detecting sensory inputs that come from craniofacial region. ganglia house cell bodies three branches nerve: ophthalmic (V1), maxillary (V2), mandibular (V3). These connect to second-order neurons brainstem nuclear complex. Trigeminal neuralgia one most prevalent types facial discomfort. characterized by abrupt, fle...

Trigeminal neuralgia is characterized by paroxysmal episodes of facial pain in the distribution of the trigeminal nerve. It can occur in either sex but is most frequently seen in women aged 50-60 years. This article presents case of trigeminal neuralgia in a 55-year-old female patient caused by meningioma of petroclival localization. The article underscores the importance of neurologic and neur...

Background; Trigeminal Neuralgia: It is a syndrome characterised by recurrent sudden & usually unilateral severe brief stabbing. One more branches of 5th cranial nerve are causing pain. painful, experience. Pain can occur spontaneously be triggered innocuous stimuli like yawning, chewing, light touch, other transmitted stimuli. divided different lengths pain-free intervals, Aim and objectiv...

Our purpose is to report a case of trigeminal neuralgia caused by vertebrobasilar dolichoectasia treated with microvascular decompression. A 63-year-old man sought treatment for a recurrent lancinating left facial pain in V2 and V3 trigeminal territories. The computed tomography angiography revealed a mechanical compression of the left trigeminal nerve due to vertebrobasilar dolichoectasia. The...

A cluster-tic syndrome: a case report 2 ARC Publishing Introduction Cluster headache is characterized by unilateral, recurrent, short-lived severe pain in the orbito-temporal area along with ipsilateral autonomic symptoms (lacrimation, rhinorrhea). Trigeminal neuralgia is characterized by recurrent, unilateral attacks of sharp, stabbing pain in the sensory innervation of one or more trigeminal ...

BACKGROUND Trigeminal neuralgia (TN) is a common cause of facial pain. PURPOSE To answer the following questions: 1) In patients with TN, how often does routine neuroimaging (CT, MRI) identify a cause? 2) Which features identify patients at increased risk for symptomatic TN (STN; i.e., a structural cause such as a tumor)? 3) Does high-resolution MRI accurately identify patients with neurovasc...

Trigeminal neuralgia (TN) is defined as sudden, usually unilateral, severe, brief, stabbing recurrent episodes of pain within the distribution of one or more branches of the trigeminal nerve. It is the most frequent cranial neuralgia, the incidence being 1 per 1,000,00 persons per year. Pain attacks start abruptly and last several seconds but may persist 1 to 2 minutes. The attacks are initiate...

Detection of external irritants by head nociceptor neurons has deep evolutionary roots. Irritant-induced aversive behavior is a popular pain model in laboratory animals. It is used widely in the formalin model, where formaldehyde is injected into the rodent paw, eliciting quantifiable nocifensive behavior that has a direct, tissue-injury-evoked phase, and a subsequent tonic phase caused by neur...

Trigeminal pain represents one of the worst pains that humans can suffer. One of the obstacles towards development of rationally targeted therapies is rooted in shortcomings of available animal models for trigeminal pain. Another roadblock is lack of clear understanding of molecular and cellular mechanisms that underlie this type of pain. TRPV4 is a polymodally activated Ca-permeable nonselecti...