Patients with Alzheimer's disease (AD) have heterogeneous rates of disease progression. The aim of the current study is to investigate whether neuropsychiatric disturbances predict cognitive and functional disease progression in AD, according to failure theory. We longitudinally examined 177 memory-clinic AD outpatients (mean age = 73.1, SD = 8.1; 70.6% women). Neuropsychiatric disturbances at ...

Neuroscientists have defined a subtype of Alzheimer’s disease (AD) that they say is neither well recognized nor appropriately treated. The variant, called hippocampal sparing AD, comprised 11% of the 1,821 AD-confirmed brains examined by Mayo Clinic researchers, suggesting that this AD subtype is relatively widespread in the general population. Individuals with hippocampal sparing AD are mostly...

Atopic dermatitis (AD) is a complex disease with elevated risk of respiratory comorbidities. Severely affected patients are often treated immune-modulating systemic drugs. On March 11th 2020, the World Health Organization declared 2019 novel coronavirus severe acute syndrome (SARS-Cov-2) epidemic to be pandemic. The number cases worldwide increasing exponentially and poses major health threat, ...

Introduction: Functional brain networks show small-world properties. As a disconnection syndrome, Alzheimer’s disease (AD) shows the significant functional disconnection between brain regions. In addition, AD subjects also evidence different small-world properties when compared to normal subjects [1-2]. The small world is connected by many smaller modules. In the present study, we tested a hypo...

Atopic is the most common of the dermatitides seen in infancy and childhood, but there are numerous other diseases that can mimic the skin findings. These include seborrheic dermatitis, immunodeficiency, and psoriasis in infancy; scabies, tinea corporis infection, perioral, nummular, contact, and molluscum dermatitis in childhood. It is sometimes extremely difficult to differentiate between ich...

Atopic dermatitis (AD) is one of the most common chronic relapsing in lammatory skin and allergic diseases [1-3]. AD refers to socially signi icant diseases. This disease retains its clinical signs for many years, it is often transformed into bronchial asthma with a severe atopic syndrome or into a systemic disease damaging not only the skin, but also internal organs such as digestive, respirat...

Obesity, also named as New World Syndrome, is emerging as a frequent global health issue with increasing incidence rate and exercise influence over the world. Recent researches have shown that obesity was associated with levels of ghrelin and leptin hormones, vitamin D deficiency, SMAM-1 avian adenovirus, Canine distemper virus (CDV), Rous-associated virus-7 (RAV-7), Borna disease virus (BDV), ...

The neuroanatomic specificity with which Alzheimer's disease (AD) progresses could provide clues to AD etiopathology. Magnetic resonance imaging studies of AD clinical progression have confirmed general conclusions from earlier studies of AD neuropathological progression wherein neurofibrillary tangle pathology was observed to spread along a well-defined sequence of corticocortical and corticos...