Glucose and lipids are important nutrients because they provide enough energy for cell activity. However, the human body takes in too much glucose lipids, will cause obesity, diabetes some other metabolism diseases. Adipose tissue exerts crucial roles regulating whole-body metabolic through its storage secretion function. Exosomes a family of extracellular vesicles released by all types that ai...

Adipose tissue is an abundant source of mesenchymal stem cells, which have shown promise in the field of regenerative medicine. Furthermore, these cells can be readily harvested in large numbers with low donor-site morbidity. During the past decade, numerous studies have provided preclinical data on the safety and efficacy of adipose-derived stem cells, supporting the use of these cells in futu...

The aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. Rat large intestine was dissected in fragments and decellularized by physicochemical methods. The scaffolds were loaded by human adipose derived mesenchymal stem cells expressing green fluorescent protein. Microscopic sections were prepared fr...

PURPOSE To identify pluripotential stem cells from human orbital adipose depots. METHODS Pluripotential adipose-derived stem cells were isolated from human orbital adipose during routine blepharoplasty surgery. Fresh adipose tissue was separated in nasal fat and central (preaponeurotic) fat. Individual adipose depots were minced, enzymatically digested, and plated on plastic culture dishes. A...

The repair of peripheral nerve injury has always been a difficult clinical problem. Although variety treatment methods are available in practice, their efficacy is limited. In recent years, the components carried by adipose stem cell exosomes and functions have increasingly discovered. A large number experiments conducted around world shown that adipose-derived positive effect on injury. This a...

Smooth muscle differentiated adipose tissue-derived stem cells are a valuable resource for regeneration of gastrointestinal tissues, such as the gut and sphincters. Hypoxia has been shown to promote adipose tissue-derived stem cells proliferation and maintenance of pluripotency, but the influence of hypoxia on their smooth myogenic differentiation remains unexplored. This study investigated the...

To address the functionality of diabetic adipose-derived stem cells in tissue engineering applications, adipose-derived stem cells isolated from patients with and without type II diabetes mellitus were cultured in bioreactor culture systems. The adipose-derived stem cells were differentiated into adipocytes and maintained as functional adipocytes. The bioreactor system utilizes a hollow fiber-b...

Objective: Arsenic, an environmental pollutant, decreases neuronal migration as well as cellular maturation and inhibits the proliferation of neural progenitor cells. Curcumin has been described as an antioxidant and neuroprotective agent with strong therapeutic potential in some neurological disorders. Human adipose-derived stem cells (hADSCs), a source of multipotent stem cells, can self-rene...

Introduction and purpose: Wound healing is a process including complex overlapping stages requiring many components. Adipose tissue an organ that responsible for maintaining homeostasis through inflammatory responses, signal transmission, energy expenditure connected with different organs. Fat rich readily available source of multipotent stem cells. Adipose-derived cells (ADSCs) have the potent...