In Canada, people diagnosed with active tuberculosis (TB) disease are routinely treated with isoniazid, rifampin, pyrazinamide and ethambutol. Although effective, the treatment is associated with significant adverse drug reactions (ADRs). Current knowledge of these ADRs has focused on their frequency and clinical natures [1, 2]. However, reporting clinical natures of ADRs is not adequate to ful...

Background and Objectives: Pharmacovigilance is central to the control of the menace of adverse drugs reactions. Despite the fact that development of policy and practice framework to improve patients’ safety partly rely on availability of authentic data on pharmacovigilance activities, knowledge about pharmacovigilance activities among healthcare professionals in Nigeria is limited. To help fil...

BACKGROUND Recent studies have shown that adverse drug reactions (ADRs) are underreported. This may be particularly true of ADRs associated with complementary and alternative medicine (CAM). Data on CAM-related ADRs, however, are sparse.Objective was to evaluate the impact of an educational intervention and monitoring programme designed to improve physician reporting of ADRs in a primary care s...

BACKGROUND The objective of analysis of ADRs caused by drugs that pertain to the ATC group N (nervous system), as reported to the Croatian Agency for Medicinal Products and Medical Devices for the period from March 2005 to December 2008, was to examine the types of ADRs collected in said period, the profile of reporters and the possible impacts this could have on prescribing this group of medic...

BACKGROUND & OBJECTIVES Several studies have reported adverse drug events ranging from 5 to 35 per cent in all age group from outpatient setting. However, adverse drug reactions (ADRs) particularly among a large sample of ambulatory elderly patients in India has not been reported. This study has attempted to identify ADRs and assessed their causality, preventability and severity, and also their...

OBJECTIVE With the use of any drug comes the possibility of unintended consequences which when harmful are referred to as adverse drug reactions (ADRs). The development of national pharmacovigilance systems is the responsibility of all health workers. The aim of this study was to investigate the knowledge of nurses about pharmacovigilance and attitudes about ADR and adverse event reporting. M...

BACKGROUND Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England. We examined trends in hospital admissions associated with adverse drug reaction in English hospitals and the accuracy of national reporting. METHODS Data from the Hospital Episode Statistics databa...

People in every country of the world are affected by adverse drug reactions (ADR) and it is estimated that at least 60% of ADRs are preventable (WHO fact sheet). Data from various studies have shown that about 20 80% of ADRs are preventable. Majority of hospitals in India do not have an ADR reporting and monitoring programme. Moreover, assessment of the impact and potential for prevention was l...

AIMS To explore the usefulness of data derived from observational studies on adverse drug reactions (ADRs) in defining and preventing the risk of pharmacological interventions in children in different health care settings. METHODS A systematic review of studies on ADRs in hospitalized children, in outpatient children, and on ADRs causing paediatric hospital admissions was performed. Studies w...

Adverse drug reactions (ADRs) till date are still considered as one of the main problems therapy. Pharmacovigilance is monitoring safety by means spontaneous adverse-effect reporting systems, case control and cohort studies.
 This study evaluated levels awareness knowledge pharmacovigilance (i.e., ADR reporting) amongst final year students Rivers State College Health Science Technology, Po...