BACKGROUND Numerous observational studies suggest that preventable adverse drug reactions are a significant burden in healthcare, but no meta-analysis using a standardised definition for adverse drug reactions exists. The aim of the study was to estimate the percentage of patients with preventable adverse drug reactions and the preventability of adverse drug reactions in adult outpatients and i...

This study investigated the occurrence and characteristics of adverse drug reactions (ADR) in our hospital and provide references for clinical rational drug use. We collected the 85 case reports of adverse drug reactions in our hospital in 2010 and made retrospective statistical analysis on them. The varieties of anti-infective drugs used are the most used. It also had the highest proportion of...

background : following establishment of iranian adverse drug reaction (adr) monitoring  center  in  1997, adr  committees  were  established  in  all  hospitals  of mazandaran province of iran. clinical pharmacists from mazandaran university of medical sciences have been involved with these committees since 2007. the aim of this study was to compare the results of the pharmacovigilance system b...

introduction: amodiaquine is a partner drug in the artemisinin-based combination therapy artesunate-amodiaquine. reports of the adverse drug reaction known as amodiaquine-associated asthenia are scarce, and this adverse reaction needs to be investigated in detail. this article presents and reviews a case of amodiaquine-associated asthenia. a literature search for the characteristics of this adv...

BACKGROUND It has been claimed that the risk of adverse drug reactions increases with age. However, only limited data exist for disease-group specific risks and none for patients with liver and gastrointestinal diseases. AIMS To determine the incidence and characteristics of adverse drug reactions and the physicians' awareness of adverse drug reactions. METHODS During a 7-month period, a pr...

OBJECTIVES To evaluate the pattern of immunosuppressive drug adverse reactions in adult kidney transplant recipients in Iran. MATERIALS AND METHODS Adult kidney transplant outpatients under immunosuppressive therapy were recruited into the study. All adverse drug reactions to immunosuppressants and their relevant clinical and paraclinical characteristics were recorded. Causality assessment wa...

leukotriene receptor antagonists(montelukast) have been used for many years in the treatment of asthma both acute and chronic stages. they are accepted commonly as safe but mostly possible side effects are ignored. however, montelukast also could lead to important adverse reactions like hallucinations. in literature only 2 reports have been found about hallucinations with it. one is a study whi...