نتایج جستجو برای: adverse drug reactions adrs
تعداد نتایج: 850498 فیلتر نتایج به سال:
A study of adverse drug reactions due to antihypertensive drugs in a tertiary care teaching hospital
Adverse drug reactions (ADRs) present a serious public health problem that can affect patients, caregivers, pharmaceutical companies, and the health care system as a whole. The objective of the present study was to evaluate Adverse Drug Reactions associated with antihypertensive drugs. The present study was an open, non-comparative, observational study was done to monitor ADRs associated with a...
BACKGROUND There is no publicly available resource that provides the relative severity of adverse drug reactions (ADRs). Such a resource would be useful for several applications, including assessment of the risks and benefits of drugs and improvement of patient-centered care. It could also be used to triage predictions of drug adverse events. OBJECTIVE The intent of the study was to rank ADRs...
In recent years, pharmacovigilance has undergone some major changes. First, the patient's active role in identifying and describing adverse drug reactions (ADRs) has gained recognition. Second, pharmacovigilance has increasingly incorporated information and communications technology (ICT). Patients can now upload their own reports of ADRs online. Data on intensive medication monitoring are now ...
background : adverse drug reactions (adr) are ranked as some of the major causes of patient morbidity and mortality. spontaneous reporting of adrs has remained the cornerstone of pharmacovigilance and is important in maintaining patient safety. this study was conducted to assess the nurses’ knowledge and attitude towards pharmacovigilance, reasons for not reporting adrs, and their pharmacovigil...
Artemisinin-based combination antimalarial therapy (ACTs), is still highly effective in uncomplicated falciparum malaria, however, there remain some concerns in relation to its safety and tolerability. Comorbid disease conditions may influence susceptibility to adverse drug reactions (ADRs) as the presence of multiple disease conditions may predisposes patients to ADRs due to the use of many me...
Under the Adverse Drug Reactions Information Scheme (ADRIS) data and knowledge relevant to the etiology of adverse drug reactions (ADRs) such as chemical structure of parent compounds, metabolites, covalent adducts, nucleic acid and protein sequences, protein structures, pharmaco-, toxico- and enzyme kinetics, pharmaco- and toxicodynamics, protein interactions, molecular pathways and complexes,...
INTRODUCTION Anticancer drugs contribute significantly to the global burden of adverse drug reactions (ADRs). Any attempt to quantify their magnitude and provide upgraded knowledge would help oncologists in writing safer prescriptions. AIM This observational follow-up study was conducted on newly diagnosed cancer patients receiving anticancer therapy with an aim to determine the frequency, se...
The growing significance of bioinformatics and systems biology in drug safety research requires a system of adverse-event classification that goes beyond a simple vocabulary. This opinion piece outlines the need for development of an ontology-based framework of describing adverse drug reactions (ADRs) and describes the potential applications for such a framework.
background: adverse drug reactions (adrs) are one of the leading causes of morbidity and mortality and contribute to excessive health care costs. detection and reporting of adrs could decrease these consequences. the present study was designed to assess the knowledge, attitude and practice (kap) of pharmacy students towards adrs monitoring and reporting. methods: a questionnaire was prepared to...
Unwanted side effects of drugs are a burden on patients and a severe impediment in the development of new drugs. At the same time, adverse drug reactions (ADRs) recorded during clinical trials are an important source of human phenotypic data. It is therefore essential to combine data on drugs, targets and side effects into a more complete picture of the therapeutic mechanism of actions of drugs...
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