The atomic force microscope (AFM) is emerging as a powerful tool in cell biology. Originally developed for high-resolution imaging purposes, the AFM also has unique capabilities as a nano-indenter to probe the dynamic viscoelastic material properties of living cells in culture. In particular, AFM elastography combines imaging and indentation modalities to map the spatial distribution of cell me...

Determination of nano particle size is substantial since the nano particle size exerts a significant effect on various properties of nano materials. Accordingly, proposing non-destructive, accurate and rapid techniques for this aim is of high interest. There are some conventional techniques to investigate the morphology and grain size of nano particles such as scanning electron microscopy (SEM)...

Serious cases of corrosion of metallic structures under both alternating current (ac) and cathodic protection (cp) have been reported. The objective of this research is to propose a mechanism by which ac affects the nano sized/structured surface films formed on metals under cp. A model will be proposed and experimentally validated, in order to relate the metal corrosiveness to its nano sized/st...

Membrane tension underlies a range of cell physiological processes. Strong adhesion of the simple red cell is used as a simple model of a spread cell with a finite membrane tension-a state which proves useful for studies of both membrane rupture kinetics and atomic force microscopy (AFM) probing of native structure. In agreement with theories of strong adhesion, the cell takes the form of a sph...

through PeakForce QNMTM, 3) correlated nanoscale AFM-based conductivity measurements are a powerful technique for nanometer-scale electrical characterization on a wide range of samples. Traditionally, these measurements have been categorized into two classes: Conductive AFM (CAFM), which covers the higher current range (sub-nA up to μA), and Tunneling AFM (TUNA), which covers the lower current ...

INTEGRATION OF Ag2Ga NANONEEDLES ON BATCH FABRICATED MICRO-GRIPPERS FOR MATERIAL PROPERTY MEASUREMENT PengXu March 22, 2011 In this thesis self-assembled growth of Ag2Ga nano-needles on batch fabricated micro-grippers are reported. The room temperature growth of Ag2Ga nano-needles have been recently developed as stylus for Atomic Force Microscopy (AFM). Integration of such nano-needles onto bat...

Advances in microscopy have contributed to many biologic discoveries. Electron microscopic techniques such as cryo-electron tomography are remarkable tools for imaging the interiors of bacterial cells in the near-native state, whereas optical microscopic techniques such as fluorescence imaging are useful for following the dynamics of specific single molecules in living cells. Neither technique,...

Nanoscale science and technology has today mainly focused on the fabrication of nano devices. In this paper, we study the use of lithography process to build the desired nanostructures directly. Nanolithography on polymethylmethacrylate (PMMA) surface is carried out by using Atomic Force Microscope (AFM) equipped with silicon tip, in contact mode. The analysis of the results shows that the ...