Normal ageing is associated with a decline in episodic memory, and neuroimaging studies in older adults have shown reduced activity in prefrontal cortex and other regions critical for memory function in the young. However, older adults also activate additional regions, suggesting a degree of functional reorganisation that has been attributed variously to detrimental and adaptive changes. Evalua...

INTRODUCTION Non-pharmacological therapies for normal ageing and dementia are a set of treatment programmes intended to improve the performance of cognitive processes, improve emotional well-being, promote independence in daily life activities, and ultimately increase patients' quality of life. METHODS We applied a battery of tests assessing four major domains (general mental state, emotional...

Ageing in humans is typified by the decline of physiological functions in various organs and tissues leading to an increased probability of death. Some individuals delay, escape or survive much of this age-related decline and live past age 100. Studies comparing centenarians to average-aged individuals have found polymorphisms in genes that are associated with long life, including APOE and FOXO...

Ageing is intrinsically complex, being driven by multiple causal mechanisms. Each mechanism tends to be partially supported by data indicating that it has a role in the overall cellular and molecular pathways underlying the ageing process. However, the magnitude of this role is usually modest. The systems biology approach combines (i) data-driven modelling, often using the large volumes of data...

The changes that occur in the human voice due to ageing have been well documented. The impact of these changes on speaker verification is less clear. In this work, we examine the effect of long-term vocal ageing on a speaker verification system. On a cohort of 13 adult speakers, using a conventional GMM-UBM system, we carry out longitudinal testing of each speaker across a time span of 30-40 ye...

Large amounts of mineral oil are used in electrical equipments as insulation and cooling medium. To avoid damages and cut-off of power electricity supply it is necessary to evaluate the mineral oil condition. Lifetime estimation of mineral oil which is based on accelerated thermal ageing at three temperatures (according to IEC 60216-1/2001) requires a long experimental time. This standardized m...

Data of optical performance, thermal stability and ageing are given for solar selective coatings (SSC) based on a novel MoSi2-Si3N4 absorbing composite. SSC have been prepared as multilayer stacks formed by silver as metallic infrared reflector, a double layer composite and an antireflective layer (doi: 10.1016/j.solmat.2016.04.001 [1]). Spectroscopic reflectance data corresponding to the optic...

The "glucocorticoid cascade hypothesis" for pathological ageing of the brain is supported by strong experimental data, but the clinical correlates are far less clear. The basal ACTH and cortisol secretion have been studied before and after the dexamethasone suppression test in patients in the early stages of clinically probable Alzheimer's disease and in controls, and the results were all norma...

introduction: regarding the increasing number of elderly people, their quality of life becomes more important. spiritual well-being is one of the most important aspects of health status which has often been neglected in some nations. this study aims to identify the relationship between spiritual well-being and quality of life among the elderly people residing of zahedan city in 2016. methods: t...