Background: Basosquamous carcinoma (BSC) is a rare non-melanoma skin cancer, considered to be a subtype of basal cell carcinoma (BCC). BSC often produces distant metastases with a higher risk of recurrence than that of BCC which is not commonly found in the lip. Case Report: A 57-year-old white female patient presented an ulcer on her lower lip that had an ongoing development for over six month...

Dear Editors, Skin cancers are a very common malignancy. According to American Cancer Society estimates, more than 70 000 new cases of invasive melanoma and more than 53 000 new cases of melanoma in situ will have occurred in the USA by the end of 2011 (1). However, the annual incidence of non-melanoma skin cancers, such as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is more d...

The aim of this study was to analyze the scope of pre-surgical high resolution ultrasound in basal cell carcinoma (BCC). BCC is the most common human cancer. According to recent large prospective studies incomplete excision of BCC is higher than expected. Pre-operative imaging may aid surgical planning by identifying the extent and location of a neoplasm, which can be interesting at zones with ...

To cite: Garg M, Sharma P, Gupta S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200180 DESCRIPTION We report a case of 30-year-old woman presented with giant, foul smelling ulcerated growth involving the vulva. The growth was involving the whole of labia majora, minora and adjacent skin associated with itching, bleeding and discharge (figure 1). The...

BACKGROUND Actinic keratosis (AK) is a well-established precancerous skin lesion that has the potential to progress to squamous cell carcinoma (SCC). Basal cell carcinoma (BCC) is a locally aggressive slowly growing tumour that rarely metastasizes. A number of viruses have been proposed to play a role in the development of nonmelanoma skin cancers (NMSC), but the most plausible evidence to date...

Background: Immune response is key in defense against basal cell carcinoma (BCC). We aim to better define the immune tumor microenvironment this cancer. Methods: CD8+ infiltrating lymphocytes (TILs) obtained from fresh BCC specimens nodular subtype (“nBCC”, n=6) versus infiltrative (“iBCC”, were subject single-cell RNA profiling. Data analyzed using iCellR. Results: TILs clustered based on gene...

BACKGROUND Solid organ recipients are at an increased risk of developing various malignancies. We investigated the incidence, clinical features, and outcome of patients diagnosed with head and neck cancer after organ transplantation. METHODS A retrospective analysis was undertaken of patients who underwent solid organ transplantation (kidney, liver, lung, heart) treated at our institution fro...

In the theory of rings, the properties of derivations are important. In [15], Jun and Xin applied the notion of derivations in ring and near-ring theory to BCI-algebras, and they also introduced a new concept called a regular derivation in BCI-algebras. They investigated some properties of its .In this manuscript, the concept of fuzzy left (right) derivations BCCideals in BCC-algebras is introd...

Non-melanoma skin cancer (NMSC) is the most common type of worldwide, being subdivided in two types: basal cell carcinoma (BCC) and squamous (SCC). SCC more aggressive than BCC, triggering severe health aesthetic complications. Among non-invasive therapies to treat SCC, Photodynamic therapy (PDT) 5-Fluorouracil (5-FU) are frequently employed clinic. PDT uses a photosensitizing agent which prese...

Smoothened antagonists directly target the genetic basis of human basal cell carcinoma (BCC), the most common of all cancers. These drugs inhibit BCC growth, but they are not curative. Although BCC cells are monomorphic, immunofluorescence microscopy reveals a complex hierarchical pattern of growth with inward differentiation along hair follicle lineages. Most BCC cells express the transcriptio...