Introduction: The use of vegetable proteins as ingredients in food systems is based on their functional properties. water and oil holding capacity, foaming, emulsifying capacity/stability, antioxidant assay the protein fractions - albumins, globulins 7S/11S, glutelins prolamins isolated from Leucaena seed were evaluated. Objective: objective this study was to evaluate properties capacity concen...

Nitrogranulogen (NTG) may modify the character of inflammatory reactions. These modifications are a result of cytotoxic and mutagenic effects. NTG has high affinity to DNA and causes disorders in the synthesis of acute phase proteins (e.g., haptoglobin, transferrin, fibrinogen, and complement protein C3). Our previous studies have shown that small doses of NTG can enhance immunological defense ...

A fluorescent dye library approach for the development of a bioanalyte sensor was sought. The screening of a rosamine dye library against diverse macromolecules led to the discovery of a highly sensitive human serum albumin binder, G13, with approximately 36-fold fluorescence intensity change. G13 showed a highly selective response to HSA over other macromolecules including albumins from other ...

To determine whether equilibrium binding between albumin and hepatocytes involves a cell surface receptor for albumin, we incubated freshly isolated rat hepatocytes with 125I-albumin and determined the amount of albumin associated with the cells as a function of the total albumin concentration. The resulting two-phase binding curve showed the rat albumin-hepatocyte interaction to consist of a s...

I n one of our publications we reported about the diffusion kinetics attendant upon the introduction of equine I-tagged albumin into the rabbit cornea. The average transfer coefficient out of the cornea for this protein was at that time calculated to be 0.09 to 0.11 per day. Recently, in preparing new material for publication relating rate constants for both equine albumin and gamma globulin by...

A comparative study of serum biochemical and hematological parameters from Andinoacara rivulatus Ichthyoelephas humeralis in Los Ríos Province, Ecuador, was carried out. Two the native species that are most commercialized Quevedo, Mocache Fumisa, were identified; 60 specimens captured each area (180 total). factorial design (3×2) used: three habitat zones (Fumisa, Mocache) two (A. I. humeralis)...

The aim of this work was to study the interaction of sulpiride with human serum albumin (HSA) and bovine serum albumin (BSA) through the fluorescence quenching technique. As sulpiride molecules emit fluorescence, we have developed a simple mathematical model to discriminate the quencher fluorescence from the albumin fluorescence in the solution where they interact. Sulpiride is an antipsychotic...

The focus of DMPK Theme Issues is state of the art and recent developments in research areas that have significant relevance for the academic world as well as for the pharmaceutical industry. The three issues that have appeared to date deal with drug-metabolizing enzymes, membrane transporters and pharmacokinetics and phar-macodynamics. This issue is dedicated to a water-soluble protein transpo...