نتایج جستجو برای: alcoholic cirrhosis
تعداد نتایج: 58498 فیلتر نتایج به سال:
Background: Alcoholic cirrhosis is second leading indication for liver transplantation in United States and Europe. The spectrum of alcohol related liver injury varies from simple steatosis to cirrhosis; patients with alcoholic cirrhosis have high prevalence of complications at the time of cirrhosis diagnosis. So there is a need to study the radiology and underlying biochemical changes for earl...
Adult human liver biopsies were cultured from normal, alcoholic hepatitis, chronic active hepatitis, fibrosis plus alcoholic hepatitis (active cirrhosis), inactive cirrhosis, and drug hepatitis. The synthesis of collagen was estimated in cultures from 58 livers by measuring the conversion of [(14)C]proline to the [(14)C]hydroxyproline of collagen; that of glycosaminoglycans in cultures from 57 ...
BACKGROUND Cystic fibrosis-related liver disease (CFLD) is present in up to 30% of cystic fibrosis patients and can result in progressive liver failure. Diagnosis of CFLD is challenging. Non-invasive methods for staging of liver fibrosis display an interesting diagnostic approach for CFLD detection. AIM We evaluated transient elastography (TE), acoustic radiation force impulse imaging (ARFI),...
OBJECTIVE There are evidences that the changes in glycosylation and sialylation of proteins and lipids play an important role in the pathogenesis and progression of various liver diseases. The aim of this study was to evaluate the changes in the sialylation of serum lipids measured by the level of lipid-bound sialic acid (LSA) in liver diseases of different etiologies. MATERIALS AND METHODS T...
BACKGROUND The risk of alcohol-related liver cirrhosis increases with increasing alcohol consumption, but many people with very high intake escape from liver disease. We postulate that susceptibility to alcoholic cirrhosis has a complex genetic component and propose that this can be dissected through a large and sufficiently powered genomewide association study (GWAS). METHODS The GenomALC Co...
A group of 258 patients with various forms of alcoholic liver disease-steatosis, mild and severe hepatitis, and cirrhosis-has been studied. Severity of disease as judged histologically did not correlate very well with clinical presentation although signs of hepatocellular failure were certainly commoner in severe hepatitis and cirrhosis. Fever, pigmentation, and clubbing were also pointers to t...
Plasma progesterone was raised in 36 of 50 (72%) men with liver disease compared with 20 healthy male control subjects. Plasma progesterone was significantly higher in men with non-alcoholic cirrhosis with gynaecomastia than those without, but no similar relationship was found in men with alcoholic fatty change and alcoholic cirrhosis. Hyperprolactinaemia was found in 14% of men with liver dise...
Alcoholic cirrhosis is a common condition that can lead to serious complications. The locations of varicose veins such as the anorectal area, the colon, the bladder or the ileal area have been reported more frequently in patients with portal hypertension associated with portal vein thrombosis and with cirrhosis. Several authors have described these varices in relation to the bile duct, but the ...
Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirrhosis. The exact pathogenesis of alcoholic liver injury is still not clear but...
Background: Alcoholic liver cirrhosis is a life-threatening condition, especially in patients who are unable to reduce their alcohol use. Alcohol abuse closely linked low socioeconomic status and social marginalization. In Japan, public assistance (PA) or Seikatsu-hogo ensures medical care for low-income populations. This study aimed investigate the potential excess mortality among with alcohol...
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