نتایج جستجو برای: all bfm
تعداد نتایج: 1882139 فیلتر نتایج به سال:
BACKGROUND AND OBJECTIVES Early treatment response is a strong predictor for treatment outcome in childhood acute lymphoblastic leukemia (ALL), treated within the protocols of the Berlin-Frankfurt-Münster (BFM) study group. In the ALL-BFM trials, early treatment response is assessed by in vivo response to glucocorticoids (prednisone response), the molecular background of which is unknown. Initi...
Between April 1985 and March 1987 130 children and adolescents up to 18 years of age with first relapse of acute lymphoblastic leukemia (ALL) were registered on the stratified and randomized multicentric trial ALL-REZ BFM 85 designed for patients pretreated with intensive front-line therapies. Stratification criteria were time and site of relapse: bone marrow (BM) relapse on or up to 6 months a...
background: women engaged with polycystic ovarian syndrome (pcos), as the commonest endocrine disorder, are known to have a specific type of adiposity. birth weight is among different contributors reported to be responsible for this diversity. objective: we aimed to compare the relation between birth weight and body fat mass (bfm)/ body lean mass (blm) in pcos and their age and body mass index ...
One hundred ninety-eight children and adolescents were entered in the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)-ALL95 study for highrisk acute lymphoblastic leukemia (ALL). Inclusion criteria were poor response to initial prednisone/intrathecal methotrexate (prednisone-poor response [PPR]), resistance to induction therapy, translocation t(9;22), infants with the t(4;11...
La leucemia linfoblástica aguda constituye la neoplasia infantil más frecuente. Los tratamientos posibilitan del 80% de supervivencia libre enfermedad por cinco años. En el 2000, se probó protocolo quimioterapia ALLIC BFM. Utilizando metodología PRISMA, sistematizó información acerca los pacientes pediátricos con tratados uso BFM en sus versiones 2002 o 2009. global donde utilizó fue 52% al 91,...
The pharmacogenetics of methotrexate (MTX) was investigated in a large cohort of pediatric patients with acute lymphoblastic leukemia (ALL). Four hundred ninety-nine children with ALL from the ALL-BFM (Berlin-Frankfurt-Münster) 2000 trial who received 1996 courses of MTX at 5 g/m(2) were genotyped for 8 single nucleotide polymorphisms in 5 candidate genes of the MTX/folate pathway. Patients' MT...
The prognostic value of MRD in large series of childhood T-ALL has not yet been established. Trial AIEOP-BFM-ALL 2000 introduced standardized quantitative assessment of MRD for stratification, based on immunoglobulin and TCR gene rearrangements as polymerase chain reaction targets: Patients were considered MRD standard risk (MRD-SR) if MRD was negative at day 33 (time point 1 [TP1]) and day 78 ...
Background & objectives: Recently, fitness (bodyweight workout), kickboxing and TRX training have become very popular. The aim of the present study was to determine the effect of a period of fitness-kickboxing and fitness-TRX training on some anthropometric indices and cardiovascular risk factors in overweight women. Methods: Forty overweight women were randomly divided into three groups. The ...
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