Treatment of wounds is very important and was subject of different investigations. In this regard, natural substance plays crucial role as complementary medicine. Various studies reported that aloe vera has useful effects on wounds especially cutaneous wounds healing. Therefore in the current review, we examined the effect of aloe vera on cutaneous wound healing and concluded that although aloe...

BACKGROUND The herbal preparation, aloe vera, has been claimed to have anti-inflammatory effects and, despite a lack of evidence of its therapeutic efficacy, is widely used by patients with inflammatory bowel disease. AIM To perform a double-blind, randomized, placebo-controlled trial of the efficacy and safety of aloe vera gel for the treatment of mildly to moderately active ulcerative colit...

BACKGROUND/OBJECTIVE Recently, it was confirmed that the daily oral intake of plant sterols of Aloe vera gel (Aloe sterol) significantly increases the skin barrier function, moisture, and elasticity in photoprotected skin. This study aimed to investigate whether Aloe sterol intake affected skin conditions following sunlight exposure in Japanese men. METHODS We performed a 12-week, randomized,...

Aloe vera gel exhibits protective effects against insulin resistance as well as lipid-lowering and anti-diabetic effects. The anti-diabetic compounds in this gel were identified as Aloe-sterols. Aloe vera gel extract (AVGE) containing Aloe-sterols has recently been produced using a new procedure. We previously reported that AVGE reduced large-sized intestinal polyps in Apc-deficient Min mice fe...

Antioxidative potential of Aloe was studied in mice exposed to different doses of gamma radiation. In this study, adult male Swiss albino mice were divided in six groups (I, II, III, IV, V and VI). Group I and II contained sham irradiated (normal) and Aloe alone treated animals respectively. Each group from III-VI contained an experimental set in which Aloe extract was administered orally at th...

BACKGROUND With the increasing incidence of periodontal diseases and development of antibiotic resistance, the global need for alternative treatment modalities, safe, effective, and economical products is the need of time. Aloe vera is a medicinal plant which has the greater medicinal value and enormous properties for curing and preventing oral diseases disease. AIM The aim of the study was t...

Developing multifaceted, biocompatible, artificial implants for tissue engineering is a growing field of research. In recent times, several works have been reported about the utilization of biomolecules in combination with synthetic materials to achieve this process. Accordingly, in this study, the ability of an extract obtained from Aloe vera, a commonly used medicinal plant in influencing the...

BACKGROUND In Korea, Aloe is routinely ingested as a traditional medicine or as a component of health beverages. OBJECTIVE To research the inhibition of indoleamine 2, 3-dioxygenase (IDO) activities of components from Aloe. MATERIALS AND METHODS the compounds were isolated by a combination of silica gel and YMC Rp-18 column chromatography, and their structures were identified by analysis of...

PURPOSE Many systemic and topical therapeutic agents such as growth hormone, platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), epidermal growth factor (EGF), and insulin-like growth factor (IGF) have been used as vulnerary agents. However, the role of nitric oxide (NO) as a wound-healing stimulant has been received with mixed reviews. NO is a potent vasodilator that is thou...

The aloes of Ethiopia and Eritrea are moderately diverse. Edwards et al (1997) recognised 38 species, including Aloe vituensis which has yet to be located north of Ethiopia’s border with Kenya, so it is not, as yet, an Ethiopian Aloe. The most recent complete survey of aloes in Ethiopia and Eritrea (Sebsebe Demissew & Nordal, 2010) recognised 46 species, again including A. vituensis. Since that...