BACKGROUND Malignant pleural effusion (MPE) is a common complication in most malignancies. Despite its frequent occurrence, current knowledge of MPE remains limited and the effect of the management is still unsatisfying. Traditional Chinese medicine (TCM) external treatment has unique advantages, such as quicker efficacy and fewer side effects. OBJECTIVE To observe the effects and safety of K...

A female in her late 20s was diagnosed with systemic atopic dermatitis in another hospital 5 years earlier and treated by steroid ointment application to the affected areas and oral steroid administration. She visited our hospital due to the aggravation of dermatitis symptoms over the entire face from 1 week earlier. Lesions were present on the face, chest, neck, and bilateral upper limbs, and,...

Jing Wan Hong ointment contains 30 kinds of Chinese herbs, with functions of activating blood circulation to disperse blood stasis, clearing heat, eliminating dampness, and reducing swelling by detoxification. Therefore, Jing Wan Hong ointment may facilitate the healing of ulcers. The aim of this study was to evaluate the efficacy and mechanisms of Jing Wan Hong ointment for healing diabetic fo...

OBJECTIVE To investigate the effect of 5-fluorouracil (5-FU) ointment on the inner ear of guinea pigs. STUDY DESIGN AND SETTING In group A (n = 7), 5-FU ointment was applied into the left external auditory canal. In group B (n = 10), 5-FU ointment was applied to the left middle ear through myringotomy. In both groups, the right ear served as a control. One week later the endocochlear DC poten...

Atopic dermatitis often requires long-term treatment. This European, multicentre, non-comparative, 24-month, follow-up study investigated the efficacy and safety of 0.1% tacrolimus ointment applied to adults with atopic dermatitis. Patients (n=672) applied a thin layer of 0.1% tacrolimus ointment twice daily for 3 weeks to all affected body areas. After 3 weeks, ointment was applied once daily....

10.2217/14750708.2.3.343 © 2 part of Psoriasis is a common skin condition that causes significant morbidity. Treatments can be complex and time consuming. Calcipotriol plus betamethasone dipropionate ointment (Daivobet® or Dovobet®) is a stable, convenient, once-daily topical treatment for psoriasis. Compared with its individual ingredients or tacalcitol, it has a faster speed of onset and grea...

The wound healing effect of methanolic extract of the root of aegle marmelos was evaluated in the form of an ointment with two different concentrations (5% and 10% w/w in simple ointment base) in excision wound model and incision wound model in rats. In both the concentrations, the extract ointment produced a significant response in both the wound types tested, as evidenced by its wound contrac...

Rice Bran wax is obtained from natural sources and is abundantly available in the country. Rice bran wax is suitable for use in chocolate enrobes, as an enteric coating for candy and lozenges, as a plasticizing material in chewing gums etc. Present study attempts to find if rice bran wax is useful as ointment base. The oleaginous type ointment base is prepared by using rice bran wax and evaluat...

BACKGROUND Tacrolimus (formerly FK 506) is an immunosuppressive drug that works by inhibiting calcineurin, a calcium-dependent protein phosphatase required for immune function. Tacrolimus has been shown to be effective topically in atopic dermatitis and systemically in psoriasis and graft-vs-host disease (GVHD). However, its efficacy in treating cutaneous GVHD when applied topically has not bee...

The evaluation of wound healing activity was conducted to study the effect of various extracts of Carmona retusa (Vahl) Masam. The ointment was prepared from the alcohol extract of root, stem and leaves with petroleum jelly as a base in 5% and 10% concentrations. Swiss albino mice were used for the evaluation of wound healing activity. The ointment prepared from various parts exhibited consider...