High oxygen concentrations induced visual cell degeneration in albino and pigmented rabbits. The most sensitive cells were located in the area centralis, a zone analogous to the human macula, and characterized by low glycogen content and rich choroidal blood supply. Electron microscopy demonstrated early pathological changes of intracellular membranes followed by total disorganization of visual...

BACKGROUND Some studies have shown potential benefit of vitamin E on platelet function, but several clinical trials failed to show improved cardiovascular outcome with alpha-tocopherol supplementation. Gamma-tocopherol, a major dietary form of vitamin E, may have protective properties different from those of alpha-tocopherol. OBJECTIVE We compared the effects of supplementation with alpha-toc...

Oxygen-induced retinopathy (OIR) was produced by subjecting newborn albino rats to a 60% oxygen atmosphere for 14 days before they were killed and retinal analysis was done. The extent of OIR was measured by estimating the severity of retinal vasoobliteration in ink-perfused flat-mounted retinas. This was done with the aid of a digitizing camera and an image-analysis system designed to create b...

BACKGROUND Conflicting results from vitamin E intervention studies suggest supplemental vitamin E malabsorption. OBJECTIVE We compared vitamin E bioavailability from a supplement with that from a fortified breakfast cereal. DESIGN Vitamin E bioavailability was evaluated by using deuterium-labeled all-rac-alpha-tocopherol in three 4-d trials (2 wk apart). Five fasting subjects sequentially c...

The disposition of fluid given by i.v. infusion can be studied by fitting one-volume and two-volume kinetic models to the fractioned dilution of blood haemoglobin and serum albumin concentrations over time. However, the two-volume model is sometimes associated with a high standard error in estimating the size of the secondary (peripheral) body fluid space, V2. To examine if a fixed elimination ...

A total of 180 crossbred, weanling pigs were assigned to five dietary treatment groups: 1) a basal corn-soybean meal diet formulated to current NRC recommendations, 2) basal + monosodium phosphate (2 x NRC P recommendations; P), 3) basal + alpha-tocopheryl acetate (220 IU/kg; E), 4) basal + sorbitol (1% of the diet; S) and 5) basal + PES. Dietary treatments were continued until market weight (1...

Irradiated restructured pork loins treated with rosemary-tocopherol/double-packaging had lower TBARS values than vacuum-packaged control after 10 days of refrigerated storage. The rosemary-tocopherol combination, however, had no effect on the production of sulfur volatiles responsible for the irradiation off-odor, and color changes in irradiated pork. V7/A3 double-packaging was effective in red...

Horses have an increased susceptibility to infection because of a decline in immune function with advancing age. Vitamin E has been found to play a key role in normal immune system function. The purpose of the study was to examine the effect of vitamin E supplementation on immune function and response to vaccination in older horses. Predominantly older horses (18.9 +/- 1.3 yr, range 7 to 26 yr;...

Copyright © 2016 by Journal of Korean Academy of Oral Health This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Objectives: To assess the abs...

A reversed-phase high-performance liquid-chromatographic method for the simultaneous determination of retinol, alpha-tocopherol, alpha-carotene, beta-carotene, cryptoxanthin, lutein/zeaxanthin, and lycopene is described. This method was applied to plasma measurements in healthy young and elderly subjects. The plasma, deproteinized with ethanol, is extracted twice with n-hexane. After evaporatio...