نتایج جستجو برای: alt plans
تعداد نتایج: 72782 فیلتر نتایج به سال:
BACKGROUND Alternaria species is one of the most common molds associated with allergic diseases, and 80% of Alternaria species-sensitive patients produce IgE antibodies to a major protein allergen, Alt a 1. The structure and function of Alt a 1 is unknown. OBJECTIVE We sought to obtain a high-resolution structure of Alt a 1 using x-ray crystallography and to investigate structural relationshi...
PURPOSE Pazopanib is an effective treatment for advanced renal cell carcinoma and soft-tissue sarcoma. Transaminase elevations have been commonly observed in pazopanib-treated patients. We conducted pharmacogenetic analyses to explore mechanistic insight into pazopanib-induced liver injury. EXPERIMENTAL DESIGN The discovery analysis tested association between four-digit HLA alleles and alanin...
BACKGROUND AND AIM Liver injury is estimated by serum alanine aminotransferases (ALT) levels in experimental animal models. Laboratories use various techniques to measure ALT levels including assay reagents and chemistry analyzers. VetScan VS2 (VS2) is widely used in veterinary clinics and research laboratories for highly reproducible, convenient and effective testing. Alternatively, ALT liquid...
“In April 2003, The Association for Learning Technology (ALT) celebrated its tenth anniversary and this book has been produced in order to commemorate this landmark achievement.” So speaks the Editor of this panoramic of articles by authors primarily from the United Kingdom, but also from The Netherlands and Australia, as she begins the first of eleven chapters that chronicle the evolution of l...
Alternative Lengthening of Telomeres (ALT) is a non-telomerase mechanism of telomere lengthening that occurs in about 10% of cancers overall and is particularly common in astrocytic brain tumors and specific types of sarcomas. Somatic cell hybridization analyses have previously shown that normal telomerase-negative fibroblasts and telomerase-positive immortalized cell lines contain repressors o...
Measurement of serum alanine aminotransferase (ALT) is a common, readily available, and inexpensive laboratory assay in clinical practice. ALT activity is not only measured to detect liver disease, but also to monitor overall health. ALT activity is influenced by various factors, including viral hepatitis, alcohol consumption, and medication. Recently, the impact of metabolic abnormalities on A...
The genomic organisation of two abundant larval transcript (alt) genes from the filarial nematode Brugia malayi has been defined. The products of these genes are 78% identical in amino acid sequence, and are highly expressed in a stage-specific manner by mosquito-borne infective larvae. alt-1 is present as two near-identical copies organised in an inverted repeat of approximately 7.6 kb, occupy...
In this thesis, we study the preprocessing phase of the ALT algorithm. ALT is a well known preprocessing-based speed-up technique for Dijkstra’s algorithm, which allows fast computations of shortest paths in large scale road networks. The preprocessing of the ALT algorithm has some degree of freedom, in that it must select a subset of nodes in the graph, called landmarks, that fulfill a special...
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