نتایج جستجو برای: amentoflavone
تعداد نتایج: 113 فیلتر نتایج به سال:
Flaviviruses are among the most critical pathogens in tropical regions; they cause various severe diseases developing countries but not restricted to these countries. The development of antiviral therapeutics is crucial for managing flavivirus outbreaks. Ten proteins encoded RNA. N2B–NS3pro protein complex plays a fundamental role replication and promising drug target; however, no protease inhi...
Plant biodiversity is endowed with a huge composition and variability of active molecules known for their therapeutic effects against several diseases. In this current work, phenolic compounds are subject in silico evaluation interactions six severe acute respiratory syndrome coronavirus (SARS-CoV) enzymes to evaluate the binding mode mechanism SARS-CoV-2 enzymes. Results molecular docking data...
Hypericum perforatum (St. John's wort) is well-established for its antidepressant activity throughout the world and also various other species within this genus are used in different folk medicines. Hyperforin of St. John's wort inhibited growth of cancer cell lines and the use of hypericin (another compound of H. perforatum) in cancer photodynamic therapy is proposed. Therefore, we investigate...
Byrsonima basiloba A. Juss. species is a native arboreal type from the Brazilian "cerrado" (tropical American savanna), and the local population uses it to treat diseases, such as diarrhea and gastric ulcer. It belongs to the Malpighiaceae family, and it is commonly known as "murici." Considering the popular use of B. basiloba derivatives and the lack of pharmacological potential studies regard...
We evaluated the in vitro anti-Mycobacterium tuberculosis activity and the cytotoxicity of dichloromethane extract and pure compounds from the leaves of Calophyllum brasiliense. Purification of the dichloromethane extract yielded the pure compounds (-) mammea A/BB (1), (-) mammea B/BB (2) and amentoflavone (3). The compound structures were elucidated on the basis of spectroscopic and spectromet...
Byrsonima crassa Niedenzu (Malpighiaceae) is used in Brazilian folk medicine for the treatment of diseases related mainly to gastric ulcers. In a previous study, our group described the gastric protective effect of the methanolic extract from the leaves of B. crassa. The present study was carried out to investigate the effects of methanolic extract and its phenolic compounds on the respiratory ...
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