Front Cover: In article number 2000520 by Myungeun Seo, Wonhee Lee, and co-workers, a cross-coupling reaction is utilized for polymer surface modification. Poly(chloro-p-xylylene) (parylene C) used as substrate in Pd-catalyzed Buchwald–Hartwig amination to install primary amine groups. Parylene films with microscale topography can be successfully modified chemically bonded fabricate transparent...

Chiral vicinal diamines, including 2-aminomethyl indolines and pyrrolidines, are useful as ligands for catalytic asymmetric reactions and are also found as important components of bioactive compounds. Herein is reported the first copper-catalyzed alkene diamination that occurs with high enantioselectivity. The substrate range is the broadest yet reported for this kind of intra-/intermolecular r...

Novel temperature-sensitive polymers containing glucose units in their backbone were synthesized and covalently conjugated to trypsin. A series of copolymers based on N-isopropylacrylamide (NIPAAm) and glucosyoxylethyl methacrylate (GEMA) were prepared by using 4,4'-azobis(4-cyanovaleric acid) as an initiator, which resulted in one terminal carboxylic acid group per polymer chain. The polymers ...

One of the significant on-going challenges in chemistry is the specific and convenient detection of compounds of interest in the environment. Detection of volatile organic compounds (VOCs) via chemical ‘‘sniffing’’ requires an interaction between the VOC and a detector substrate, resulting in a measurable change. Crystal inclusion of VOCs into various d and d metal complexes has been found to a...

To develop a new more accurate spectrophotometric method for detecting monoamine oxidase inhibitors from plant extracts, a series of amine substrates were selected and their ability to be oxidized by monoamine oxidase was evaluated by the HPLC method and a new substrate was used to develop a peroxidase-linked spectrophotometric assay. 4-(Trifluoromethyl) benzylamine (11) was proved to be an exc...

The authors report the synthesis of some bioactive organic compounds which could be pharmacological interest using Dioscorea praehensilis tyrosinase immobilized on calcium-alginate beads. enzymatic these involved pyruvic acid as a source carbonyl groups, ammonia and catechol. Catechol was used substrate parent compound that supplied aromatic ring carbons for reactions. structures novel synthesi...

To develop a new more accurate spectrophotometric method for detecting monoamine oxidase inhibitors from plant extracts, a series of amine substrates were selected and their ability to be oxidized by monoamine oxidase was evaluated by the HPLC method and a new substrate was used to develop a peroxidase-linked spectrophotometric assay. 4-(Trifluoromethyl) benzylamine (11) was proved to be an exc...

This study aimed to characterize cerebral perfusion in men with Klinefelter's syndrome, known to present specific deficits in language, using (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach normalization. While a perfusion asymmetry toward the left hemisphere was found in controls, perfusion was mostly symmetrical in Klinefelter patients in the upper temporal and lower parie...