When amino acid sequences are distantly related-for instance, when their identity is <0.30-it is difficult to estimate their evolutionary distance. A method called the “similarity distance method” (SD method) was developed to obtain maximum-likelihood estimates of evolutionary distance between amino acid sequences, on the basis of a given pattern of amino acid replacement. Computer simulation r...

background: the aim was to evaluate the relapse risk of vivax malaria in patients who received radical treatment in hormozgan province, a malarious area located on southeast of iran. methods: a total of 95 symptomatic vivax malaria infected patients were enrolled in urban health centers of bandar - abbas, minab, bandar-jask and bashagard districts of hormozgan province, southeast of iran from j...