The title mol-ecule, C(14)H(12)N(2)O(2), exhibits a V-shaped conformation with a dihedral angle of 59.69 (3)° between the benzene and pyridine rings. In the crystal, O-H⋯N hydrogen bonds link the mol-ecules into zigzag chains along [010].

In the title compound, C(17)H(18)N(2)O(5)S, the dihedral angle between the aromatic rings is 68.59 (10)° and the C-S-N-C torsion angle is -81.84 (18)°. The mol-ecular conformation is stabilized by an intra-molecular N-H⋯O hydrogen bond, generating an S(6) ring. In the crystal, mol-ecules are linked by C-H⋯O and O-H⋯O hydrogen bonds into a three-dimensional network.

Benzoate competes with n-amino acids for n-amino acid oxidase and thus inhibits the activity of the oxidase (l-3). Monosubstituted benzoates, depending upon the substituent, have higher and lower affinities for the oxidase than has benzoate (2). Kojic acid, a Y-pyrone, likewise competitively inhibits the oxidase (4). The present report describes the inhibition of n-amino acid oxidase by certain...

The extensive investigations on the conjugation of benzoic acid, since Wohler’s discovery in 1824 of the synthesis of hippuric acid by the animal, have failed to furnish a comprehensive and definite concept of the metabolic and chemical changes taking place when benzoic acid is introduced into the organism. No attempt has ever been made to explain why man eliminates benzoic acid almost complete...

Microbial spoilage of food causes losses of up to 40% of all food grown for human consumption worldwide. Yeast growth is a major factor in the spoilage of foods and beverages that are characterized by a high sugar content, low pH, and low water activity, and it is a significant economic problem. While growth of spoilage yeasts such as Zygosaccharomyces bailii and Saccharomyces cerevisiae can us...

Three trials were conducted to evaluate the effect of supplementation of a basal diet with benzoic acid or thymol or a mixture of essential oil blends (MEO) or a combination of benzoic acid with MEO (BMEO) on growth performance of turkey poults. Control groups were fed a basal diet. In trial 1, benzoic acid was supplied at levels of 300 and 1,000 mg/kg. In trial 2, thymol or the MEO were suppli...