The fungivorous amoeba Protostelium aurantium feeds on a wide range of fungal species. image shows amoebae digesting GFP-expressing cells the human pathogenic yeast Candida parapsilosis. For further details, readers are referred to article by Radosa et al. p. e13389 this issue.

We compared a local clustering and a cluster morphology statistic using anthrax outbreaks in large (cattle) and small (sheep and goats) domestic ruminants across Kazakhstan. The Getis-Ord (Gi*) statistic and a multidirectional optimal ecotope algorithm (AMOEBA) were compared using 1st, 2nd and 3rd order Rook contiguity matrices. Multivariate statistical tests were used to evaluate the environme...

Molecular force fields have been approaching a generational transition over the past several years, moving away from well-established and well-tuned, but intrinsically limited, fixed point charge models toward more intricate and expensive polarizable models that should allow more accurate description of molecular properties. The recently introduced AMOEBA force field is a leading publicly avail...

The dynamic cytoskeleton in Amoeba proteus is a filamentous gel network, composed mainly of F-actin microfilaments accompanied by actin binding proteins, distributed in the peripheral cortex beneath the cell membrane and around the nucleus. As well the cell shape changes as the motility primarily depend on the activity of these structures. In contrast, the endoplasm of amoeba is commonly consid...

Cytoplasm has been isolated from single amoeba (Chaos carolinensis) in physiological solutions similar to rigor, contraction, and relaxation solutions designed to control the contractile state of vertebrate striated muscle. Contractions of the isolated cytoplasm are elicited by free calcium ion concentrations above ca. 7.0 x 10(-7) M. Amoeba cytoplasmic contractility has been cycled repeatedly ...

Since Legionella pneumophila is an intracellular pathogen, entry into and replication within host cells are thought to be critical to its ability to cause disease. L. pneumophila grown in one of its environmental hosts, Acanthamoeba castellanii, is phenotypically different from L. pneumophila grown on standard laboratory medium (BCYE agar). Although amoeba-grown L. pneumophila displays enhanced...

Cell migration is a process crucial for a variety of biological events, such as morphogenesis and wound healing. Several reports have described the possible regulation of cell migration by autophagy; however, this remains controversial. We here demonstrate that mouse embryonic fibroblasts (MEFs) lacking autophagy protein 5 (Atg5), an essential molecule of autophagy, moved faster than wild-type ...

Thiourea derivatives display a broad spectrum of applications in chemistry, various industries, medicines and various other fields. Recently, different thiourea derivatives have been synthesized and explored for their anti-microbial properties. In this study, four carbonyl thiourea derivatives were synthesized and characterized, and then further tested for their anti-amoebic properties on two p...

We study generic intersection (or web) of vortices with instantons inside, which is a 1/4 BPS state in the Higgs phase of five-dimensional N = 1 supersymmetric U(NC) gauge theory on Rt×(C) ≃ R2,1×T 2 with NF = NC Higgs scalars in the fundamental representation. In the case of the Abelian-Higgs model (NF = NC = 1), the intersecting vortex sheets can be beautifully understood in a mathematical fr...