Both the variety of specific serological reactions, and the chemical heterogeneity of the immune globulins suggest that differences in the specificity of antibodies are accompanied by appropriate differences in molecular structure. Speculation on the nature of relevant structural differences has led to two alternative assumptions: either antibody molecules of different specificity have identica...

The immunological inter-relationships between hexosaminidases* of several mammals were established. Qualitative immunochemical analysis indicated similarity between the enzymes derived from man, Rhesus monkey, Iris maccaque, bovine, pig, goat and guinea-pig. Quantitation of the extent of antigenic similarity among the various species, using antigen binding assay and radioimmunoassay, correlated...

Alternative splicing increases transcriptome and proteome diversification. Previous analyses aiming at comparing the rate of alternative splicing between different organisms provided contradicting results. These contradicting results were attributed to the fact that both analyses were dependent on the expressed sequence tag (EST) coverage, which varies greatly between the tested organisms. In t...