Microtubule poisons inhibit spindle function, leading to activation of spindle assembly checkpoint (SAC) and mitotic arrest. Cell death occurring in prolonged mitosis is the first target of microtubule poisons in cancer therapies. However, even in the presence of microtubule poisons, SAC and mitotic arrest are not permanent, and the surviving cells exit the mitosis without cytokinesis (mitotic ...

A dairy farmer, aged 42, was referred for admission to hospital by the consultant physician on June 19, 1957. He complained of deterioration of vision in the past 6 weeks and said that for the past 2 weeks he had been unable to read the paper. His visual acuity on admission was 4/60 in the right eye and 1/60 in the left. He stated that he drank about 8 pints of beer a day, but his wife said tha...

The question of women‘s rights in Islam generates huge interest among Muslims and non-Muslims alike. Scholars of feminism are sharply divided on the question of women‘s status in Islam. One group associates Islam with misogyny and gender oppression, while the other celebrates the religion as a liberatory force for women. Remarkably, despite a surge in female educational attainment and conscious...

T o what extent does the separation of powers affect congressional roll call voting behavior? To answer this question, I offer a strategic model of congressional decision making that asserts members of Congress pursue public policy goals when casting roll call votes. From the equilibrium predictions of a formal model, I generate testable hypotheses by computing the expected net amount of sophis...

We present novel results that relate energy and information transfer with sensitivity to initial conditions in chaotic multi-dimensional Hamiltonian systems. We show the relation among Kolmogorov-Sinai entropy, Lyapunov exponents, and upper bounds for the Mutual Information Rate calculated in the Hamiltonian phase space and on bi-dimensional subspaces. Our main result is that the net amount of ...