Awakening heterochromatin ites in the human genome once thought to be inert structural material are brought to life in response to stress, according to results from Jolly et al. (page 25). These inactive DNA stretches are binding sites for HSF1, a transcription factor that activates individual heat shock genes and accumulates in nuclear granules after heat shock. These granules were, like HSF1,...

It has been claimed that people often prefer equity-like considerations and tend to ignore strategic aspects in fair division problems. Here, this is explored by analyzing whether or not such a behavioral disposition is evolutionarily stable. The answer, however, is ambiguous: Both, reacting to and neglecting strategic aspects can be evolutionarily stable strategies when power discrepancies are...

In this paper a new indirect approach is presented for anisotropic quadrilateral mesh generation based on discrete surfaces. The ability to generate grids automatically had a pervasive influence on many application areas in particularly in the field of Computational Fluid Dynamics. In spite of considerable advances in automatic grid generation there is still potential for better performance and...

receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes. J Mol Cell Cardiol 2001;33:1589–1606. 24. Nofer JR, van der Giet M, Tolle M, Wolinska I, von Wnuck Lipinski K, Baba HA, Tietge UJ, Godecke A, Ishii I, Kleuser B, Schafers M, Fobker M, Zidek W, Assmann G, Chun J, Levkau B. HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. J Clin Invest 2004;...

We discuss argumentation frameworks with indirect attacks, such as why-questions and supports. A whyquestion is regarded as a kind of attack relation, and a support is an answer to an un-presented why-question. Based on this idea, we construct an argumentation framework with why-questions from a pair of knowledge bases, as an instantiation of Dung’s abstract argumentation framework, and show th...

Attention is drawn to the possibility of performing monocular indirect ophthalmoscopy with a pen torch and a condensing lens when facilities for binocular indirect ophthalmoscopy are not available.

Uromodulin, also known as Tamm-Horsfall glycoprotein (THG), derived from human pregnancy urine, is a monomeric glycoprotein of 85 kDa. It is produced in the thick ascending limb (TAL) and early distal convoluted tubule (DCT) and is excreted in large amounts in urine. The immunosuppressive property of Uromodulin is based on its glycosylation pattern that is different THG obtained from males and ...

We argue that Anselm’s ontological argument (or at least one reconstruction of it) is based on an empirical version of Berry’s paradox. It is invalid, but it takes some understanding of trivalence to see why this is so. Under our analysis, Anselm’s use of the notion of existence is not the heart of the matter; rather, trivalence is. Anselm’s ‘proof’ of the existence of God goes like this: I hav...