ion can be defined as “ignoring or hiding details to capture some kind of commonalitybetween different instances” (Free On-line Dictionary of Computing).26 Human Societies: Understanding Observed Social Phenomena713

Review methods MEDLINE, EMBASE/Excerpta Medica, Scopus, Cochrane Library (CENTRAL) (all to Nov 2012), clinicaltrials.gov, Google, abstracts from 2006 to 2012 annual meetings of the Infectious Diseases Society of America and other professional meetings, and reference lists of relevant studies were searched for published and unpublished randomized and nonrandomized controlled trials. 7 studies (n...

(Fam Med 2003;35(4):241-2.) Editor’s Note: In this month’s column, George Henning, MD, and John George, PhD, of Penn State University Department of Family Medicine, discuss evidence-based medicine instruction to medical students “in the field.” I welcome your comments about this feature, which is also published on the STFM Web site at www.stfm.org. I also encourage all predoctoral directors to ...

Authors’ Affi liations: Department of Pathology, and Brain Tumor Center, The University of Texas M.D. Anderson Cancer Center, Houston, Texas Corresponding Authors: Kenneth D. Aldape, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030. Phone: 713-792-0634; Fax: 713-745-4049; E-mail: kaldape@mdanderson. org; and Krishna P.L. Bhat, [email protected] ...

A native interactor scaffolds and stabilizes toxic Ataxin-1 oligomers in SCA1 1 C.A. Lasagna-Reeves, M.W.C. Rousseaux, M.J. Guerrero-Munoz, J. Park, 2 P. Jafar-Nejad,R. Richman, N. Lu, U.Sengupta, A. Litvinchuk, 3 H.T. Orr, R. Kayed and H.Y. Zoghbi * 4 5 1 Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030 6 2 Jan and Dan Duncan Neurological Research Insti...

(Fam Med 2007;39(1):13-5.) Editor’s Note: In this month’s column, Hershey Bell, MD, of the Lake Erie College of Osteopathic Medicine discusses the importance of giving formative feedback to learners. He proposes a mnemonic FED to remind us of the appropriate content (feedback and direction) and an effective manner of communication (encouragement). I welcome your comments about this feature, whi...

Translocator protein (TSPO) is a biomarker for detecting neuroinflammation by PET. 11C-(R)-PK11195 has been used to image TSPO since the 1980s. Here, we compared the utility of four 11C-labeled ligands-(R)-PK11195, PBR28, DPA-713, and ER176-to quantify TSPO in healthy humans. For all of these ligands, BP ND (specific-to-non-displaceable ratio of distribution volumes) was measured by partially b...

We study the cyclical behavior of economic fundamentals for value and growth firms. Our goal is to evaluate the empirical relevance of recent rational theories of the value premium. We find that the fundamentals of value firms are more adversely affected by negative business cycle shocks than those of growth firms. And the differential response is mostly significant. We also examine the potenti...