Ane-Pad (A 2358, Astra Lakemedel AB), a new local anesthetic formulation for application to the skin has been tested in the removal of split skin grafts. Ane-Pad is a thin cotton pad, containing a solution of 10% ketocaine base in a solvent mixture of isopropanol, glycerol and water. The pad has been used on the donor sites of 173 patients with a minimum application time of 1 h before surgery. ...

Investigation of recently synthesized suit[3]ane and similar systems shows that photoinduced electron transfer occurs on the picosecond time scale from encapsulated heterocycle to pyridinium-based cage.

In the title compound, C(15)H(13)NO(3)S(2), the dithiol-ane ring adopts a twisted conformation. The mol-ecule exhibits a V-shaped conformation, with a dihedral angle of 79.05 (7)° between the benzene ring and the pyridine ring. In the crystal, C-H⋯O inter-actions are observed.

Rhenium complex []Cl with the coordinated [11]ane-P(2)C(NHC) macrocycle was obtained by a metal template controlled ring formation reaction; in this reaction a coordinated NH,NH-stabilised imidazolidin-2-ylidene ligand was connected via the nitrogen atoms to two phenyl substituents of a 2-fluorophenyl substituted diphosphine ligand.

This article is a study of the ASOR society, based on database compiled from 2017 annual meeting at Boston, one largest meetings in its history. Such has not been performed before. We research as represented by roles scholar-members (poster presenters, lecture and session chairs), their subjects (geographic areas, periods, topics), affiliations (gender institutions). The analysis leads to sever...

Abstract Therapeutic radiation can result in substantially different survival outcomes for patients with non-small cell lung cancer (NSCLC). Measures identification of who benefit most throughout radiotherapy remain limited. In this retrospective study, analysis was performed based on a discovery cohort from TCGA and validation three independent hospitals. Tumor mutational burden (TMB) chromoso...

In the title compound, C(13)H(22)N(4)O(2)S(2), the six-membered ring displays a half-chair conformation. The olefin amine unit is close to being coplanar with the imidazolidine ring (r.m.s. deviation = 0.059 Å). The dithiol-ane ring adopts a twisted conformation. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions.