OBJECTIVE An aneurysm is an inflammatory vascular condition. Phosphatidylinositol 3-kinases δ is highly expressed in leukocytes, and play a key role in innate immunity. However, the link between phosphatidylinositol 3-kinases δ and aneurysm development has not yet been elucidated. APPROACH AND RESULTS Carotid ligation unexpectedly induced characteristic aneurysm formation beneath the ligation...

Mycotic aortic aneurysms are exceedingly uncommon in infants and they have a high risk of rupture. Their surgical management is extremely challenging. We report a case of a 22-month-old girl who presented with abdominal pain and fever revealing a ruptured mycotic aneurysm of the infrarenal aorta. The surgical treatment consisted of a ligature of the proximal and distal ends of the aneurysm. Pos...

Rabbit Elastase Aneurysm Model We read the interesting report by Dai et al, wherein the authors examined histology at the basilar terminus (BT) following right common carotid artery (RCCA) ligation as a part of a procedure to create an elastase aneurysm model in 30 consecutive New Zealand white rabbits at various time points. The authors concluded that in contrast to our previous report, there ...

OBJECTIVE Visceral artery aneurysms are rare vascular malformations and the literature lacks satisfactory general information about the pathology. The aim of this study was to review our experiences in the diagnosis and treatment of visceral artery aneurysms. MATERIALS AND METHODS We retrospectively reviewed data on 10 patients who were diagnosed with visceral artery aneurysms at our institut...

We report a unique case of a celiac artery graft – duodenal fistula in a 60-year-old male, who developed upper gastrointestinal bleeding two months after initial open resection of a celiac artery aneurysm and placement of an aorto-celiac artery graft. The patient underwent successful repair of the fistula and the resection of the involved graft with ligation of the common hepatic artery and spl...

Mycotic aneurysm of the abdominal aorta is an uncommon disease that carries a high mortality rate. In this report, two patients with this disease are presented. In the first case, Salmonella sp was cultured from an atherosclerotic aneurysm, and in the second patient, the aneurysm was a complication of Staphylococcus aureus bacterial endocarditis. Both presented suggestive clinical findings of t...

385 Aneurysmal dilation of AVF is due to the complex interplay between biologic factors like needle injury that induce outward wall remodeling, and physical factors such as wall tension that is directly proportional to intraaccess pressures. In a series of patients who underwent minimally invasive limited ligation endoluminal-assisted revision banding, pressure within the mid-fistula was reduce...

Aneurysms of the petrous portion of the internal carotid artery are rare lesions. One case is reported here and 18 others have been found in the literature. These lesions usually arise in young men who present with auditory dysfunction. The aneurysm is usually discovered as a pulsating purple mass in the middle ear and mistaken for a glomus jugulare tumor. A definitive diagnosis can be made by ...

BACKGROUND The A5 segment aneurysms of the anterior cerebral artery are rare, approximately 0.5% of all intracranial aneurysms. They are small with a wide base located in the midline, with the domes mostly projecting upward or backward. CASE DESCRIPTION The authors describe a unique case of A5 segment aneurysm, with the dome embedded into the body of the corpus callosum. This 41-year-old fema...

Correspondence and requests for reprints to James I. Fann, MD, Department of Cardiothoracic Surgery, Falk Cardiovascular Research Center, Stanford University Medical School, Stanford, California 94305-5247, USA. Tel: þ1 650 858 3917; fax: þ1 650 723 7110; e-mail: [email protected] Introduction Since the incidence of thoracic aortic aneurysms are over five cases per 100 000 person-years, patien...