Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon skin disease that presents as papules or nodules in the head and neck region. The pathogenesis of vascular proliferation characterizes ALHE unclear, neoplastic reactive etiologies have both been proposed. Several human polymaviruses (HPyV), including HPyV6, HPyV7, trichodysplasia spinulosa polyomavirus (TSPyV), Merkel Cell (MCPyV...

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare clinicopathologic entity that shares both clinical and histopathological features with Kimura disease. Although they were once considered as different stages of the same disease, they are now known to represent separate entities. ALHE is a condition that causes swellings in the head and neck region affecting muscular arteries and is b...

Purpose: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disorder presenting with solitary or multiple nodules in the dermis or subcutaneous tissues. ALHE shares clinical as well as histopathological characteristics with Kimura disease (KD), but they have been considered to be two distinct entities based on their histological features. Orbital and adnexal involvement in ALHE is rar...

Angiolymphoid hyperplasia with eosinophilia is a rare vascular proliferation characterized by single or multiple purplish, brownish papules and subcutaneous nodules, sometimes associated with pain or pruritus. This rare benign process occurs with a female predominance. Approximately 85% of the lesions occur in the skin of the head and neck; most of them are around the ear or on the forehead or ...

Angiolymphoid hyperplasia with eosinophilia (ALHE), also known as epithelioid hemangioma, is a chronic, benign vascular proliferation for which no cases of malignant transformation have been reported to date. Spontaneous resolution has been described in some patients, particularly in those with small lesions. ALHE is characterized by a high rate of recurrence (approximately 30%), regardless of ...

Epithelioid hemangioendothelioma is an uncommon malignant vascular tumour usually involving soft tissue and rarely only skin. It is considered to be a borderline neoplasm between angiolymphoid hyperplasia with eosinophilia and an epithelioid angiosarcoma and is mostly found in adults with few cases reported in children. We herein report a case of ulcerated cutaneous epithelioid hemangioendothel...

BACKGROUND Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon benign lesion, primarily occurring in the head and neck. ALHE arising from the ocular adnexa is rare, and the bilateral presentation is especially rare in the eyelids. CASE PRESENTATION A 64-year-old Japanese man presented with tearing. Multiple nodules, approximately 5 mm in size, were observed in bilateral upper an...