نتایج جستجو برای: angiotensin receptors
تعداد نتایج: 271145 فیلتر نتایج به سال:
The symposium “New Clinical Trials of Angiotensin Blockade in Cardiovascular Disease” was held on May 19, 1999 at the Marriott Marquis Hotel in New York, NY. It was sponsored by Novartis Pharmaceuticals and chaired by Stevo Julius, Professor of Medicine and Physiology, University of Michigan Medical Center, Ann Arbor, MI and consisted of five 25-minute long lectures. Stevo Julius pointed out th...
The existence and the properties of angiotensin II receptors in the adult bovine and human corpus callosum (CC) were investigated by using Xenopus oocytes and primary glial cell cultures. In oocytes injected with CC mRNA, angiotensin II elicited oscillatory Cl- currents due to activation of the inositol phosphate/Ca(2+)-receptor-channel coupling system. The receptors expressed in oocytes and in...
losartan potassium is a well known orally active non-peptide angiotensin ii receptor antagonist. losartan potassium and its principle active metabolites block the vasoconstrictor and aldosterone secreting effect of angiotensin ii by selectively blocking the binding of angiotensin ii to at1 receptors. the drug is reported to promote the decrease in ventricular hypertrophy, salt and water excreti...
Losartan potassium is a well known orally active non-peptide angiotensin II receptor antagonist. Losartan potassium and its principle active metabolites block the vasoconstrictor and aldosterone secreting effect of angiotensin II by selectively blocking the binding of angiotensin II to AT1 receptors. The drug is reported to promote the decrease in ventricular hypertrophy, salt ...
The adrenal cortex plays a key role in the regulation of metabolism, salt and water homeostasis sex differentiation by synthesizing glucocorticoid, mineralocorticoid androgen hormones. Evidence exists that angiotensin II regulates adrenocortical function it has been contended peptides non-canonical branch renin system (RAS) might also modulate steroidogenesis adrenals. Thus, aim this review is ...
Angiotensin II and endothelin-1 activate their respective AT(1) and ET(A) receptors on vascular smooth muscle cells, producing vasoconstriction, and both peptides are implicated in the pathogenesis of essential hypertension. Angiotensin II potentiates the production of endothelin, and conversely endothelin augments the synthesis of angiotensin II. Both AT(1) and ET(A) receptor antagonists lower...
Abstract Global outbreak of coronavirus disease 2019 (COVID-19) in December has affected millions people around the world. This virus binds to angiotensin-converting enzyme-2 receptors present pharynx, nose, oral cavity, salivary glands, tongue, etc. Saliva been shown have viral loads COVID-19 as it reported be 2019-novel-coronavirus nucleic acid positive. article is based on association fluids...
Type 2 bradykinin (B2)-receptor antagonists have been used to define the role of endogenous kinin peptides. However, interpretation of the effects of B2-receptor antagonists has been limited by lack of information concerning the effects of these antagonists on endogenous kinin and angiotensin peptide levels. If kinin levels were subject to short-loop-feedback regulation mediated through B2 rece...
BACKGROUND Although the renin-angiotensin and the beta-adrenergic systems are interrelated, a direct interaction between beta-adrenergic receptors (betaARs) and angiotensin II type 1 receptors (AT1Rs) has not been identified. METHODS AND RESULTS Here, we provide evidence for a functional and physiological interaction between 2 G protein-coupled receptors: the betaAR and the AT1R. Selective bl...
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