نتایج جستجو برای: animal testing alternatives
تعداد نتایج: 580515 فیلتر نتایج به سال:
Background-Parameters of cardiopulmonary exercise testing (CPX) were recently identified as
BACKGROUND Skin prick test (SPT) is a common test for diagnosing immunoglobulin E-mediated allergies. In clinical routine, technicalities, human errors or patient-related biases, occasionally results in suboptimal diagnosis of sensitization. OBJECTIVE Although not previously assessed qualitatively, lancet weight is hypothesized to be important when performing SPT to minimize the frequency of ...
U.S. Mine Safety and Health Administration (MSHA) regulations require underground coal mines to use refuge alternatives (RAs) to provide a breathable air environment for 96 hours. One of the main concerns with the use of mobile RAs is heat and humidity buildup inside the RA. The accumulation of heat and humidity can result in miners suffering heat stress or even death. MSHA regulations require ...
BACKGROUND Liver transplantation is a life-saving intervention for many patients with end-stage liver disease. In the past, evaluation of successful liver transplantation was based on patients' survival rate. However, in recent years this evaluation has been based on patients' quality of life. Various instruments have been developed to evaluate patients' quality of life. Nonetheless, scholars s...
Regulatory authorities require safety and potency testing prior to the release of each production lot of acellular pertussis (aP)-containing vaccines. Currently, the murine histamine sensitization test (HIST) is used to evaluate the presence of residual pertussis toxin in aP containing vaccines. However, the testing requires the use of a significant number of mice and results in unrelieved pain...
Read-across as a non-animal testing alternative for the generation of risk assessment data can be useful in those cases where quantitative structure-activity relationship (QSAR) models are not available, or are less well developed. This paper provides read-across case studies for the estimation of the aquatic toxicity of five different fragrance substances, and proposes a pragmatic approach for...
The Scientific Community, concerned about animal welfare, is sensitive to concerns regarding how and why animals are used in biomedical research and testing to evaluate the toxicological potential of various substances. Although alternatives to methods based on the use of animals may not satisfy all requirements and needs of the biomedical research and toxicologic testing communities, alternati...
The Scientific Community, concerned about animal welfare, is sensitive to concerns regarding how and why animals are used in biomedical research and testing to evaluate the toxicological potential of various substances. Although alternatives to methods based on the use of animals may not satisfy all requirements and needs of the biomedical research and toxicologic testing communities, alternati...
The scientific community is sensitive to concerns about how and why animals are used in biomedical research and testing. Although alternatives to methods based on the use of animals may not satisfy all the requirements of the biomedical research communities, alternatives to the use of vertebrates have been developed and validated. Research on such methodologies is aimed at refining procedures t...
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