P-selectin blocking potency was investigated using synthetic monomeric and polymeric anionic compounds containing sulfate groups such as O-sulfotyrosine (sTyr) and/or sulfated Lewis structures. A non-carbohydrate-containing polyacrylamide conjugate sTyr-PAA (80% mol of sTyr) was a remarkably potent inhibitor of P-selectin binding in vitro, having an IC(50) value of 6 ng/mL (equivalent to 10 nM ...

The stability mechanism and thermal properties of the system alumina-anionic polyacrylamide (PAM) was studied. The polymer's adsorption properties in dependence on the following parameters solution pH (in the range 3-9), temperature (in the range 15-35 °C), and carboxyl groups' content in the PAM chains (in the range 5-30 %) were examined. The turbidimetry method was applied for determination o...

The aim of this paper is to investigate the effects of hydrogel mesh size, a conductive polymer, and electric field strength on controlled drug delivery phenomena using drug-loaded polyacrylamide hydrogels prepared at various crosslinking ratios both with and without a conductive polymer system. Poly(p-phenylene vinylene), PPV, as the model conductive polymer, was used to study its ability to c...

The apparent diffusion coefficients, Dapp, and the release mechanisms of Aloin-doped poly(phenylene vinylene)/polyacrylamide hydrogels, Aloin-doped PPV/PAAM, were investigated. In the absence of an electric field (passive release), the diffusion of Aloin from the SA-doped PPV/PAAM hydrogel is delayed in the first 36 hr due to the ionic interaction between the anionic drug and PPV. Beyond this p...

This laboratory study examines the potential use of an anionic polyacrylamide (PAM)-based material as environmentally sustainable additive for stabilization expansive soil from South Australia. The experimental program consisted consistency limits, sediment volume, compaction and oedometer cyclic swell–shrink tests, performed using distilled water four different PAM-to-water solutions P D = 0.1...

High molecular weight, linear polyacrylamide (PAM) with anionic charge is added to agricultural soils as an anti-erosion additive. Research indicates that soil microorganisms are able to utilize PAM as a source of N and that inorganic N pools are altered in some PAM-treated soils. The potential role of hydrdlytic amidase activity in the microbial utilization of PAM for N was investigated. Intra...

Due to the importance of nanoparticles stability in industrial applications, in this research, stability of laponite nanoparticles dispersions containing different concentrations of sodium sulfonated polyacrylamide (SPA) was investigated in electrolyte media for oil reservoirs applications. In this regard, effect of parameters such as polymer concentration, temperature, and ionic strength were ...

Soil structural stability is a vital aspect of soil quality and functions, maintaining sustainable land management. The objective this study was to compare the contribution four long-term land-use systems (crop, bush, grass, forest) coupled with anionic polyacrylamide (PAM = 0, 25, 200 mg L?1) application on soils in three watersheds Ethiopia varying elevation. Effect treatments indices were as...