Recently, we showed that titanocene silyls are much more stable with Ti in the oxidation state +3. The current study demonstrates that analogous Zr and Hf compounds can also be obtained by reaction of a suitable metalate precursor with an oligosilanyl dianion. As the obtained complexes formally possess a d(1) electron configuration, they were investigated using EPR spectroscopy. The correspondi...

•Unprecedented zirconocene catalysis in reductive ring opening of epoxides•Broad reactivity across diverse substrates, including natural products•Reverse regioselectivity compared with the well-established methods titanocene•Changing metal center metallocene alters reversibility Epoxides are key structural motifs commonly found products and medicinal agrochemical agents as well various intermed...

A titanocene-catalyzed multicomponent coupling to provide diarylethynyl methanes is described. By combining the multifunctionality of Cp(2)TiCl(2) with the traceless dielectrophilicity of aryl aldehydes, all-carbon tertiary centers are obtained in 55-99% yield.

Endoscopic treatment of pancreatic ductal malformations causing recurrent acute pancreatitis, such as pancreas divisum or ansa pancreatica, is mainly based on the sphincterotomy of the minor papilla. However, the technical complexity of conventional endoscopic retrograde cholangiopancreatography (ERCP) is increased in patients presenting anatomical variants like these and it may be unsuccessful...

A paper to submit for International Workshop on Object-Oriented Real-Time Dependable Systems. This article discusses the extension of a distributed object-based paradigm the ANSA Architecture and its example implementation ANSAware for real-time applications. It reviews some of early experiences in the design, implementation and performance evaluation of two ANSA-based real-time system environm...

Prostate cancer is the most common malignant disease in men. Several therapeutic agents have been approved during the last 10 years. Among them, radium-223 dichloride (Xofigo®) is a radioactive isotope that induces irreversible DNA double-strand breaks and consequently tumor cell death. Radium-223 dichloride is a calcium-mimetic agent that specifically targets bone lesions. Radium-223 dichlorid...

In this paper we describe the production and consumption of linked data in the scenario of the Italian news agency ANSA portal. The goal of the use-case is to provide viewers of a news item with background information and links to related news articles contained on the portal. This information enrichment process is entity-based: ANSA news archive is analyzed using Name Entity Recognition, and e...

Distributed systems has been an area of intense activity over the past ten years. The subject is entering a stage of maturity with work now focussing on standards for Open Distributed Processing (ODP). However, it is important that standardisation is responsive to new demands on the technology. This is especially true with the emergence of high speed networks in general and multimedia computing...